Excitatory Postsynaptic Potentials - Drug effects
Research News and Information

Saturday, November 21, 2009

Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord.

19 Oct 2009 Pure NMDA receptor (NMDAr)-mediated EPSCs, thought to correspond to "silent" glutamatergic synapses that lack AMPA receptors (AMPArs), have been observed in superficial spinal dorsal horn of neonatal but not adult rats. Recent anatomical studies ... Read more...

Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord.

19 Oct 2009 Coactivation of spinal alpha(2)-adrenergic receptors (ARs) and opioid receptors produces antinociceptive synergy. Antinociceptive synergy between intrathecally administered alpha(2)AR and opioid agonists is well documented, but the mechanism ... Read more...

Endocannabinoid-dependent homeostatic regulation of inhibitory synapses by miniature excitatory synaptic activities.

19 Oct 2009 Homeostatic regulation of synaptic strength in response to persistent changes of neuronal activity plays an important role in maintaining the overall level of circuit activity within a normal range. Absence of miniature EPSCs (mEPSCs) for a few ... Read more...

Latest indexed articles for 'Excitatory Postsynaptic Potentials - Drug effects'

These are the very latest articles for this heading:

• Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord. 19 Oct 2009
• Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord. 19 Oct 2009
• Endocannabinoid-dependent homeostatic regulation of inhibitory synapses by miniature excitatory synaptic activities. 19 Oct 2009
• Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. 12 Oct 2009
• Input-specific intrasynaptic arrangements of ionotropic glutamate receptors and their impact on postsynaptic responses. 12 Oct 2009
• Differential effects of topiramate on prefrontal glutamatergic transmission when combined with raclopride or clozapine. 29 Sep 2009
• High-affinity kainate receptor subunits are necessary for ionotropic but not metabotropic signaling. 22 Sep 2009
• Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. 22 Sep 2009
• Differential involvement of beta3 integrin in pre- and postsynaptic forms of adaptation to chronic activity deprivation. 14 Sep 2009
• The timing of external input controls the sign of plasticity at local synapses. 4 Sep 2009
• Approach sensitivity in the retina processed by a multifunctional neural circuit. 4 Sep 2009
• Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. 4 Sep 2009
• Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation. 30 Aug 2009
• Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? 24 Aug 2009
• Cortical inhibitory cell types differentially form intralaminar and interlaminar subnetworks with excitatory neurons. 24 Aug 2009
• Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses. 24 Aug 2009
• Voluntary nicotine consumption triggers in vivo potentiation of cortical excitatory drives to midbrain dopaminergic neurons. 17 Aug 2009
• Effects of scorpion toxin on excitatory and inhibitory presynaptic terminals. 13 Aug 2009
• Recruitment of N-Type Ca(2+) channels during LTP enhances low release efficacy of hippocampal CA1 perforant path synapses. 11 Aug 2009
• A role for SNAP25 in internalization of kainate receptors and synaptic plasticity. 11 Aug 2009

See a longer list of these articles.

Technical information about 'Excitatory Postsynaptic Potentials'

Definition: Depolarization of membrane potentials at the SYNAPTIC MEMBRANES of target neurons during neurotransmission. Excitatory postsynaptic potentials can singly or in summation reach the trigger threshold for ACTION POTENTIALS.

Descriptor UI: D019706

Alternative terms: Excitatory Postsynaptic Potentials; Excitatory Postsynaptic Potential; Postsynaptic Potential, Excitatory; Postsynaptic Potentials, Excitatory; Potential, Excitatory Postsynaptic; Potentials, Excitatory Postsynaptic; EPSP; Excitatory Postsynaptic Currents; Current, Excitatory Postsynaptic; Currents, Excitatory Postsynaptic; Excitatory Postsynaptic Current; Postsynaptic Current, Excitatory; Postsynaptic Currents, Excitatory; End Plate Potentials; End Plate Potential; Plate Potential, End; Plate Potentials, End; Potential, End Plate; Potentials, End Plate;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G04.580.887.249; G07.265.337.900.750.199; G07.265.750.887.249; G07.700.240.900.750.199; G11.561.570.918.249; G11.561.600.835.750.199;

History Note: 98

Technical Notes: for miniature end plate potentials or miniature excitatory postsynaptic potentials coordinate with MINIATURE POSTSYNAPTIC POTENTIALS