Exons
Research News and Information

Monday, November 23, 2009

The impacts of ERCC1 gene exon VIII alternative splicing on cisplatin-resistance in ovarian cancer cells.

30 Oct 2009 Excision repair cross complementation group-1 (ERCC1) was reported to be responsible for drug resistance during cancer treatment. In this report, we first proved the existence of ERCC1 exon VIII alternative splicing in ovarian cancer cells. Further ... Read more...

Fam83h is associated with intracellular vesicles and ADHCAI.

30 Oct 2009 Defects in FAM83H on human chromosome 8q24.3 cause autosomal-dominant hypocalcified amelogenesis imperfecta (ADHCAI). FAM83H does not encode a recognizable signal peptide, so we predicted that the Fam83h protein functions within the cell. We tested ... Read more...

Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3.

17 Oct 2009 BACKGROUND: Alternative splicing (AS) of maturing mRNA can generate structurally and functionally distinct transcripts from the same gene. Recent bioinformatic analyses of available genome databases inferred a positive correlation between intron ... Read more...

Latest indexed articles for 'Exons'

These are the very latest articles for this heading:

• Tracking rates of transcription and splicing in vivo. 30 Oct 2009
• The impacts of ERCC1 gene exon VIII alternative splicing on cisplatin-resistance in ovarian cancer cells. 30 Oct 2009
• Fam83h is associated with intracellular vesicles and ADHCAI. 30 Oct 2009
• Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3. 17 Oct 2009
• Rates of in situ transcription and splicing in large human genes. 9 Oct 2009
• Characterization of conserved tandem donor sites and intronic motifs required for alternative splicing in corticosteroid receptor genes. 7 Oct 2009
• Molecular cloning and characterization of the porcine prostaglandin transporter (SLCO2A1): evaluation of its role in F4 mediated neonatal diarrhoea. 4 Oct 2009
• Further evidence for an association between mandibular height and the growth hormone receptor gene in a Japanese population. 29 Sep 2009
• Li-Fraumeni and Li-Fraumeni-like syndrome mutations in p53 are associated with exonic methylation and splicing regulatory elements. 29 Sep 2009
• Novel variants near the central domain of RYR1 in two malignant hyperthermia-susceptible families from Taiwan. 29 Sep 2009
• SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system. 27 Sep 2009
• Comparative SNP diversity among four Eucalyptus species for genes from secondary metabolite biosynthetic pathways. 22 Sep 2009
• Analysis of TACI mutations in CVID & RESPI patients who have inherited HLA B*44 or HLA*B8. 21 Sep 2009
• Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. 17 Sep 2009
• Mutations in lipase H cause autosomal recessive hypotrichosis simplex with woolly hair. 16 Sep 2009
• An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons. 15 Sep 2009
• The role of exon sequences in C complex spliceosome structure. 13 Sep 2009
• Effects of two common polymorphisms in the 3' untranslated regions of estrogen receptor beta on mRNA stability and translatability. 13 Sep 2009
• Splice site strength-dependent activity and genetic buffering by poly-G runs. 11 Sep 2009
• Exon deletions and intragenic insertions are not rare in ataxia with oculomotor apraxia 2. 9 Sep 2009

See a longer list of these articles.

Technical information about 'Exons'

Definition: The parts of a transcript of a split GENE remaining after the INTRONS are removed. They are spliced together to become a MESSENGER RNA or structural RNA.

Descriptor UI: D005091

Alternative terms: Exons; Exon; Mini-Exon; Mini Exon; Mini-Exons;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.360.340.024.340.137.232;

Online Note: search BASE SEQUENCE 1980-86

History Note: 87; was see BASE SEQUENCE 1980-86