Fatty Alcohols - Pharmacology
Research News and Information

Sunday, November 22, 2009

Marine two-headed sphingolipid-like compound rhizochalin inhibits EGF-induced transformation of JB6 P+ Cl41 cells.

3 Jul 2009 Rhizochalin [(2R,3R,26R,27R)-2,27-diamino-3-hydroxy-26-[(2R,3R,4S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy]octacosan-11-one], an antimicrobial and cytotoxic marine two-headed sphingolipid-like natural product, isolated from ... Read more...

[6]-Gingerol suppresses interleukin-1 beta-induced MUC5AC gene expression in human airway epithelial cells.

29 Jun 2009 BACKGROUND: [6]-Gingerol is a major active component of ginger and a natural polyphenol compound. The present study investigated whether [6]-gingerol suppresses interleukin (IL)-1 beta-induced MUC5AC gene expression in human airway epithelial cells ... Read more...

Early calcium increase triggers the formation of olfactory long-term memory in honeybees.

14 Jun 2009 BACKGROUND: Synaptic plasticity associated with an important wave of gene transcription and protein synthesis underlies long-term memory processes. Calcium (Ca2+) plays an important role in a variety of neuronal functions and indirect evidence ... Read more...

Latest indexed articles for 'Fatty Alcohols - Pharmacology'

These are the very latest articles for this heading:

• Marine two-headed sphingolipid-like compound rhizochalin inhibits EGF-induced transformation of JB6 P+ Cl41 cells. 3 Jul 2009
• [6]-Gingerol suppresses interleukin-1 beta-induced MUC5AC gene expression in human airway epithelial cells. 29 Jun 2009
• Early calcium increase triggers the formation of olfactory long-term memory in honeybees. 14 Jun 2009
• [6]-Gingerol suppresses colon cancer growth by targeting leukotriene A4 hydrolase. 14 Jun 2009
• Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress. 11 Jun 2009
• Topical vehicles based on natural surfactant/fatty alcohols mixed emulsifier: The influence of two polyols on the colloidal structure and in vitro/in vivo skin performance. 30 May 2009
• Differential induction of apoptosis of leukemic cells by rhizochalin, two headed sphingolipids from sponge and its derivatives. 30 May 2009
• [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. 25 May 2009
• Panaxydol inhibits the proliferation and induces the differentiation of human hepatocarcinoma cell line HepG2. 16 May 2009
• In situ seasonal study of the volatile production of almonds (Prunus dulcis) var. 'Nonpareil' and relationship to navel orangeworm. 11 May 2009
• Leukotriene B4 contributes to exhaled breath condensate and sputum neutrophil chemotaxis in COPD. 6 May 2009
• Triacontanol and jasmonic acid differentially modulate the lipid organization as evidenced by the fluorescent probe behavior and 31P nuclear magnetic resonance shifts in model membranes. 5 May 2009
• Ginger's (Zingiber officinale Roscoe) inhibition of rat colonic adenocarcinoma cells proliferation and angiogenesis in vitro. 29 Apr 2009
• Gingerol inhibits cisplatin-induced vomiting by down regulating 5-hydroxytryptamine, dopamine and substance P expression in minks. 27 Apr 2009
• Relationship between calcium release and NADPH oxidase inhibition in human neutrophils. 21 Apr 2009
• Antibacterial activity and chemical composition of essential oil of Pamburus missionis. 14 Apr 2009
• Leukotriene B4 regulates proliferation and differentiation of cultured rat myoblasts via the BLT1 pathway. 11 Apr 2009
• Two sides of a leaf blade: Blumeria graminis needs chemical cues in cuticular waxes of Lolium perenne for germination and differentiation. 6 Apr 2009
• Sugar cane policosanols do not reduce LDL oxidation in hypercholesterolemic individuals. 30 Mar 2009
• Characterization of the ileal muscarinic receptor system in 70-week-old type II Goto-Kakizaki diabetic rats; effects of cyclohexenonic long-chain fatty alcohol. 22 Mar 2009

See a longer list of these articles.

Technical information about 'Fatty Alcohols'

Definition: Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

Registry Number: 0

Descriptor UI: D005233

Alternative terms: Fatty Alcohols; Alcohols, Fatty;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.033.415; D10.289;

History Note: 72