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Fibroblasts - Cytology
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Definition of 'Fibroblasts'

Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Common names: Fibroblasts; Fibroblast

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Monday, November 23, 2009

Chk2 protects against radiation-induced genomic instability.

29 Sep 2009 The murine Chk2 kinase is activated after exposure to ionizing radiation and is necessary for p53-dependent apoptosis, but the role Chk2 plays in determining genomic stability is poorly understood. By analyzing the sensitivity of Chk2-deficient ... Read more...


High content analysis of human fibroblast cell cultures after exposure to space radiation.

29 Sep 2009 Space travel imposes risks to human health, in large part by the increased radiation levels compared to those on Earth. To understand the effects of space radiation on humans, it is important to determine the underlying cellular mechanisms. While ... Read more...


Increased oral fibroblast lifespan is telomerase-independent.

29 Sep 2009 Oral mucosal wound-healing is characterized by rapid re-epithelialization and remodeling, with minimal scar formation. This may be attributed to the distinct phenotypic characteristics of the resident fibroblasts. To test this hypothesis, we ... Read more...

 

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Technical information about 'Fibroblasts'

Definition: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Descriptor UI: D005347

Alternative terms: Fibroblasts; Fibroblast;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.329.228; A11.872.228;

History Note: 65(64)

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