Fibronectins
Research News and Information

Sunday, November 22, 2009

Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1.

29 Nov 2009 The components of the extracellular matrix (ECM) and their differential expression patterns play important roles in tissue formation. The deposition of latent TGF-beta binding proteins (LTBPs) to the ECM exhibit distinct distribution profiles. We ... Read more...

Tissue-engineered polyethylene oxide/chitosan scaffolds as potential substitutes for articular cartilage.

29 Sep 2009 Applications of composite scaffolds comprising polyethylene oxide (PEO) and chitosan to the culture of bovine knee chondrocytes (BKC) were investigated. Here, PEO and chitosan with various weight ratios were crosslinked, refrigerated at -80 degrees ... Read more...

Smooth muscle cell adhesion in surface-modified three-dimensional copolymer scaffolds prepared from co-continuous blends.

29 Sep 2009 In this article, tissue-engineering scaffolds were fabricated from P(epsilon-CL-co-D,L-LA)-PEG-P(epsilon-CL-co-D,L-LA) copolymers using co-continuous blends with polystyrene as the porogen phase. By means of static annealing and following extraction ... Read more...

Latest indexed articles for 'Fibronectins'

These are the very latest articles for this heading:

• Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1. 29 Nov 2009
• Tissue-engineered polyethylene oxide/chitosan scaffolds as potential substitutes for articular cartilage. 29 Sep 2009
• Smooth muscle cell adhesion in surface-modified three-dimensional copolymer scaffolds prepared from co-continuous blends. 29 Sep 2009
• Designing tailored biomaterial surfaces to direct keratinocyte morphology, attachment, and differentiation. 13 Sep 2009
• An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. 4 Sep 2009
• Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction. Sep 2009
• Thrombospondin-2 therapy ameliorates experimental glomerulonephritis via inhibition of cell proliferation, inflammation, and TGF-beta activation. 31 Aug 2009
• Cadherin and integrin regulation of epithelial cell migration. 30 Aug 2009
• Patterned Au/poly(dimethylsiloxane) substrate fabricated by chemical plating coupled with electrochemical etching for cell patterning. 30 Aug 2009
• ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271). 30 Aug 2009
• Prediction of spontaneous preterm birth in asymptomatic twin pregnancies with the use of combined fetal fibronectin and cervical length. 30 Aug 2009
• Fetal fibronectin as a short-term predictor of preterm birth in symptomatic patients: a meta-analysis. 30 Aug 2009
• Plasminogen activator inhibitors regulate cell adhesion through a uPAR-dependent mechanism. 30 Aug 2009
• A novel fibronectin type III module binding motif identified on C-terminus of Leptospira immunoglobulin-like protein, LigB. 19 Aug 2009
• Reduction of lysyl hydroxylase 3 causes deleterious changes in the deposition and organization of extracellular matrix. 18 Aug 2009
• High molecular weight kininogen binds to laminin--characterization and kinetic analysis. 17 Aug 2009
• Angiotensin II receptor blockade improves matrix metalloproteinases/tissue inhibitor of matrix metalloproteinase-1 balance and restores fibronectin expression in rat infarcted myocardium. 16 Aug 2009
• Characterization of cryogel monoliths for extraction of minor proteins from milk by cation exchange. 13 Aug 2009
• A novel human fibronectin cryptic sequence unmasked by the insertion of the angiogenesis-associated extra type III domain B. 13 Aug 2009
• Directed assembly of PEGylated-peptide coatings for infection-resistant titanium metal. 10 Aug 2009

See a longer list of these articles.

Technical information about 'Fibronectins'

Definition: Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.

Registry Number: 0

Descriptor UI: D005353

Alternative terms: Fibronectins; Opsonic alpha(2)SB Glycoprotein; Opsonic Glycoprotein; Glycoprotein, Opsonic; LETS Proteins; Proteins, LETS; alpha 2-Surface Binding Glycoprotein; alpha 2 Surface Binding Glycoprotein; Fibronectin; Cold-Insoluble Globulins; Cold Insoluble Globulins; Globulins, Cold-Insoluble;

Related Mesh Headings: Receptors, Fibronectin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.377.715.390; D12.776.395.550.350; D12.776.543.550.350; D12.776.860.300.450;

History Note: 80

Technical Notes: extracellular matrix proteins; /biosyn /physiol permitted