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Fluoxetine
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Definition of 'Fluoxetine'

The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.

Common names: Fluoxetine; N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine; Fluoxetin; Sarafem; Prozac; Fluoxetine Hydrochloride; Lilly-110140; Lilly 110140; Lilly110140

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Saturday, November 21, 2009

Depletion of selective serotonin reuptake inhibitors during sewage sludge composting.

30 Oct 2009 Sewage and sewage sludge is known to contain pharmaceuticals, and since sewage sludge is often used as fertilizer within agriculture, the reduction of the selective serotonin reuptake inhibitors (SSRIs) Citalopram, Sertraline, Paroxetine, ... Read more...


Antidepressant actions of histone deacetylase inhibitors.

14 Sep 2009 Persistent symptoms of depression suggest the involvement of stable molecular adaptations in brain, which may be reflected at the level of chromatin remodeling. We find that chronic social defeat stress in mice causes a transient decrease, followed ... Read more...


Randomized, controlled clinical trial of the efficacy of fluoxetine for treatment of compulsive disorders in dogs.

13 Sep 2009 OBJECTIVE: To evaluate efficacy of fluoxetine hydrochloride for treatment of compulsive disorders in dogs. DESIGN: Randomized, controlled clinical trial. ANIMALS: 63 dogs with compulsive disorders. PROCEDURES: The diagnosis was confirmed on the ... Read more...

 

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Technical information about 'Fluoxetine'

Definition: The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.

Chemical name: Benzenepropanamine, N-methyl-gamma-(4-(trifluoromethyl)phenoxy)-, (+-)-

Registry Number: 54910-89-3

Descriptor UI: D005473

Alternative terms: Fluoxetine; N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine; Fluoxetin; Sarafem; Prozac; Fluoxetine Hydrochloride; Lilly-110140; Lilly 110140; Lilly110140;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Serotonin Uptake Inhibitors; Antidepressive Agents, Second-Generation;

Tree Number: D02.092.831.280;

Online Note: use FLUOXETINE to search FLUOXETIN 1979-89

History Note: 90(79); was FLUOXETIN see under PROPYLAMINES 1979-88; was FLUOXETIN 1989

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