Free Radical Scavengers - Therapeutic use
Research News and Information

Monday, November 23, 2009

Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption.

5 Aug 2009 BACKGROUND: Panadol Osteo (GlaxoSmithKline) is a modified-release paracetamol formulation marketed in Australia and New Zealand, comprising 33% immediate and 66% sustained-release fractions. In overdose, absorption may be delayed and the paracetamol ... Read more...

Intense correlation between brain infarction and protein-conjugated acrolein.

4 Aug 2009 BACKGROUND AND PURPOSE: We recently found that increases in plasma levels of protein-conjugated acrolein and polyamine oxidases, enzymes that produce acrolein, are good markers for stroke. The aim of this study was to determine whether the level of ... Read more...

Anterior spinal artery as a collateral channel in patients with acute bilateral vertebral artery occlusions. Two case reports.

30 Jul 2009 Retrograde flow through the anterior spinal artery (ASA) from the cervical vertebral artery (VA) to the intracranial distal VA due to disrupted perfusion caused by bilateral VA occlusion is rare. We report two cases of hemodynamic vertebrobasilar ... Read more...

Latest indexed articles for 'Free Radical Scavengers - Therapeutic use'

These are the very latest articles for this heading:

• Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption. 5 Aug 2009
• Intense correlation between brain infarction and protein-conjugated acrolein. 4 Aug 2009
• Anterior spinal artery as a collateral channel in patients with acute bilateral vertebral artery occlusions. Two case reports. 30 Jul 2009
• [Molecular-targeted therapy for motor neuron disease] 30 Jul 2009
• N-acetylcysteine: multiple clinical applications. 30 Jul 2009
• Melatonin prevents cyclosporine-induced hepatotoxicity in rats. 29 Jul 2009
• Nail-biting stuff? The effect of N-acetyl cysteine on nail-biting. 29 Jun 2009
• N-acetylcysteine alters apoptotic gene expression in axotomised primary sensory afferent subpopulations. 22 Jun 2009
• Edaravone, a free radical scavenger, retards the development of amygdala kindling in rats. 19 Jun 2009
• Rationale, design, and baseline characteristics of the Acetylcystein for Contrast-Induced nephropaThy (ACT) Trial: a pragmatic randomized controlled trial to evaluate the efficacy of acetylcysteine for the prevention of contrast-induced nephropathy. 2 Jun 2009
• (S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) reduces rat myocardial apoptosis against ischemia and reperfusion injury by activation of phosphatidylinositol 3-kinase/Akt signaling and anti-inflammatory action in vivo. 18 May 2009
• Gallic acid prevents lysosomal damage in isoproterenol induced cardiotoxicity in Wistar rats. 13 May 2009
• Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy. 12 May 2009
• N-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production. 10 May 2009
• A 15-year-old girl with severe hemolytic Wilson's crisis recovered without transplantation after extracorporeal circulation with the Prometheus system. 9 May 2009
• Edaravone attenuates white matter lesions through endothelial protection in a rat chronic hypoperfusion model. May 2009
• Cardiac ischemia and reperfusion in spontaneously diabetic rats with and without application of EGb 761: II. Interstitium and microvasculature. 29 Apr 2009
• Protective effects of purified safflower extract on myocardial ischemia in vivo and in vitro. 22 Apr 2009
• Accumulation of oxidative stress around the stroke-like lesions of MELAS patients. 21 Apr 2009
• Effects of the non-peptidyl low molecular weight radical scavenger IAC in DNBS-induced colitis in rats. 17 Apr 2009

See a longer list of these articles.

Technical information about 'Free Radical Scavengers'

Definition: Substances that influence the course of a chemical reaction by ready combination with free radicals. Among other effects, this combining activity protects pancreatic islets against damage by cytokines and prevents myocardial and pulmonary perfusion injuries.

Registry Number: 0

Descriptor UI: D016166

Alternative terms: Free Radical Scavengers; Scavengers, Free Radical;

Related Mesh Headings: Free Radicals;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.217.500;

History Note: 91