GABA Agonists
Research News and Information

Saturday, November 21, 2009

Infections related to intrathecal baclofen therapy in children and adults: frequency and risk factors.

30 Oct 2009 OBJECT: The purpose of this study was to determine the frequency of infection and to identify risk factors for infection in connection with the implantation of an intrathecal baclofen (ITB) pump. METHODS: This retrospective study included all ... Read more...

Rapid use-dependent down-regulation of gamma-aminobutyric acid type A receptors in rat mesencephalic trigeminal neurons.

30 Oct 2009 Rundown is ubiquitously seen in response to repetitive activation of receptor or ion channels as a use-dependent down-regulation through various mechanisms. In contrast to AMPA receptors, gamma-aminobutyric acid type A receptor (GABA(A)R) are ... Read more...

Double dissociation and hierarchical organization of strategy switches and reversals in the rat PFC.

29 Sep 2009 Prelimbic-infralimbic cortex (PL-IL) and orbitofrontal cortex (OFC) influence behavioral flexibility in the rat. The authors tested the effects of PL-IL or OFC infusion with the GABA agonist muscimol in the context of 2 flexible responding tasks: ... Read more...

Latest indexed articles for 'GABA Agonists'

These are the very latest articles for this heading:

• Infections related to intrathecal baclofen therapy in children and adults: frequency and risk factors. 30 Oct 2009
• Rapid use-dependent down-regulation of gamma-aminobutyric acid type A receptors in rat mesencephalic trigeminal neurons. 30 Oct 2009
• Double dissociation and hierarchical organization of strategy switches and reversals in the rat PFC. 29 Sep 2009
• Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats. 9 Sep 2009
• Inbred mouse strains differ in multiple hippocampal activity traits. 2 Sep 2009
• Emerging drugs for insomnia: new frontiers for old and novel targets. 30 Aug 2009
• Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction. 23 Aug 2009
• Hibernation induces pentobarbital insensitivity in medulla but not cortex. 10 Aug 2009
• The rat prelimbic cortex mediates inhibitory response control but not the consolidation of instrumental learning. 30 Jul 2009
• Behavioral characterization of amygdala involvement in mediating intra-accumbens opioid-driven feeding behavior. 30 Jul 2009
• Temporary inactivation of ventral tegmental area neurons with either muscimol or baclofen reversibly disrupts maternal behavior in rats through different underlying mechanisms. 30 Jul 2009
• Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. 30 Jul 2009
• Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome. 30 Jul 2009
• Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. 30 Jul 2009
• GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels. 28 Jul 2009
• Clozapine, GABA(B), and the treatment of resistant schizophrenia. 20 Jul 2009
• Novel environment and GABA agonists alter event-related potentials in N-methyl-D-aspartate NR1 hypomorphic and wild-type mice. 12 Jul 2009
• Role for GABA agonists in the nucleus accumbens in regulating morphine self-administration. 8 Jul 2009
• Endogenous angiotensin II facilitates GABAergic neurotransmission afferent to the Na+-responsive neurons of the rat median preoptic nucleus. 6 Jul 2009
• [Zolpidem dependence and withdrawal seizure] 29 Jun 2009

See a longer list of these articles.

Technical information about 'GABA Agonists'

Definition: Drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA).

Registry Number: 0

Descriptor UI: D018755

Alternative terms: GABA Agonists; Agonists, GABA; gamma-Aminobutyric Acid Agonists; Acid Agonists, gamma-Aminobutyric; Agonists, gamma-Aminobutyric Acid; gamma Aminobutyric Acid Agonists; GABA Receptor Agonists; Agonists, GABA Receptor; Receptor Agonists, GABA; GABA Receptor Agonist; Agonist, GABA Receptor; Receptor Agonist, GABA; gamma-Aminobutyric Acid Agonist; Acid Agonist, gamma-Aminobutyric; Agonist, gamma-Aminobutyric Acid; gamma Aminobutyric Acid Agonist; GABA Agonist; Agonist, GABA;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Tree Number: D27.505.519.625.240.200; D27.505.696.577.240.200;

History Note: 95

Technical Notes: GEN or unspecified; prefer specifics; do not confuse with GABA ANTAGONISTS; DF: GABA AGON or GABA AG