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Galectin 3 - Metabolism
Research News and Information
Definition of 'Galectin 3'A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS. Common names: Galectin 3; CBP-30; CBP-35; CBP35; Epsilon-Binding Protein; Epsilon Binding Protein; Galectin-3; HL-29; IgE Binding Protein; Binding Protein, IgE; Protein, IgE Binding; IgEBP; L-29 Lectin; L 29 Lectin; L-31; L-34; L30 Lectin; LGALS3; Mac-2 Antigen; Antigen, Mac-2; Mac 2 Antigen |
Monday, November 23, 2009
Immunohistochemical localization of galectin-3 in the pig retina during postnatal development.
24 Sep 2009 
PURPOSE: The differential level and localization of galectin-3 protein were examined in the retinas of two-day-old pigs and six-month-old pigs. METHODS: The retinas sampled from two-day-old and six-month-old pigs were analyzed by western blot and ... Read more...
30 Aug 2009 At present, there is no efficient curative therapy for cancer patients with advanced metastatic disease. Targeting of antiapoptotic molecules acting on the mitochondrial apoptosis pathway could potentially augment antimetastatic effect of cytotoxic ... Read more...
16 Aug 2009 Previously, we showed that galectin-1 and galectin-3 are redundant pre-mRNA splicing factors associated with the spliceosome throughout the splicing pathway. Here we present evidence for the association of galectin-3 with snRNPs outside of the ... Read more...
Latest indexed articles for 'Galectin 3 - Metabolism'
These are the very latest articles for this heading:
- Immunohistochemical localization of galectin-3 in the pig retina during postnatal development. 24 Sep 2009
- Synthetic galectin-3 inhibitor increases metastatic cancer cell sensitivity to taxol-induced apoptosis in vitro and in vivo. 30 Aug 2009
- A mechanism for incorporation of galectin-3 into the spliceosome through its association with U1 snRNP. 16 Aug 2009
- Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. 10 Aug 2009
- Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. 30 Jul 2009
- Conformational entropy changes upon lactose binding to the carbohydrate recognition domain of galectin-3. 28 Jul 2009
- Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3. 4 Jul 2009
- The regulation of inflammation by galectin-3. 29 Jun 2009
- Galectin-3 regulates T-cell functions. 29 Jun 2009
- Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. 29 Jun 2009
- Galectin-3 mediates post-ischemic tissue remodeling. 28 Jun 2009
- Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier. 23 Jun 2009
- [Study on the expression and significance of Galectin-3 and CDC25B mRNA in human gastric carcinoma] 30 May 2009
- Gal-3 is stimulated by gain-of-function p53 mutations and modulates chemoresistance in anaplastic thyroid carcinomas. 29 Apr 2009
- Pulsed electron beam water radiolysis for submicrosecond hydroxyl radical protein footprinting. 30 Mar 2009
- Herpes simplex virus type 1 infection increases the carbohydrate binding activity and the secretion of cellular galectin-3. 15 Mar 2009
- Regulation of prostate cancer progression by galectin-3. 10 Mar 2009
- Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function. 11 Feb 2009
- Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Feb 2009
- Identification of matrix metalloproteinase-9 as an independent prognostic marker in laryngeal and hypopharyngeal cancer with opposite correlations to adhesion/growth-regulatory galectins-1 and -7. 30 Jan 2009
See a longer list of these articles.
Technical information about 'Galectin 3'
Definition: A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS.
Registry Number: 0
Descriptor UI: D037502
Alternative terms: Galectin 3; CBP-30; CBP-35; CBP35; Epsilon-Binding Protein; Epsilon Binding Protein; Galectin-3; HL-29; IgE Binding Protein; Binding Protein, IgE; Protein, IgE Binding; IgEBP; L-29 Lectin; L 29 Lectin; L-31; L-34; L30 Lectin; LGALS3; Mac-2 Antigen; Antigen, Mac-2; Mac 2 Antigen; Macrophage-2 Antigen; Antigen, Macrophage-2; Macrophage 2 Antigen; Carbohydrate-Binding Protein 35; Carbohydrate Binding Protein 35;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.776.503.307.300;
History Note: 2003; use GALECTIN 3 (NM) 1994-2002