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Galectin 3
Research News and Information
Definition of 'Galectin 3'A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS. Common names: Galectin 3; CBP-30; CBP-35; CBP35; Epsilon-Binding Protein; Epsilon Binding Protein; Galectin-3; HL-29; IgE Binding Protein; Binding Protein, IgE; Protein, IgE Binding; IgEBP; L-29 Lectin; L 29 Lectin; L-31; L-34; L30 Lectin; LGALS3; Mac-2 Antigen; Antigen, Mac-2; Mac 2 Antigen |
Sunday, November 22, 2009
Newer biomarkers in heart failure.
29 Sep 2009 
The pathophysiology of heart failure is complex, and the list of biomarkers representing distinct pathophysiologic pathways is growing rapidly. This article focuses on some promising newer biomarkers that have contributed to a better understanding ... Read more...
Immunohistochemical localization of galectin-3 in the pig retina during postnatal development.
24 Sep 2009 PURPOSE: The differential level and localization of galectin-3 protein were examined in the retinas of two-day-old pigs and six-month-old pigs. METHODS: The retinas sampled from two-day-old and six-month-old pigs were analyzed by western blot and ... Read more...
30 Aug 2009 At present, there is no efficient curative therapy for cancer patients with advanced metastatic disease. Targeting of antiapoptotic molecules acting on the mitochondrial apoptosis pathway could potentially augment antimetastatic effect of cytotoxic ... Read more...
Latest indexed articles for 'Galectin 3'
These are the very latest articles for this heading:
- Newer biomarkers in heart failure. 29 Sep 2009
- Immunohistochemical localization of galectin-3 in the pig retina during postnatal development. 24 Sep 2009
- Synthetic galectin-3 inhibitor increases metastatic cancer cell sensitivity to taxol-induced apoptosis in vitro and in vivo. 30 Aug 2009
- Suppression of galectin-3 expression enhances apoptosis and chemosensitivity in liver fluke-associated cholangiocarcinoma. 30 Aug 2009
- Infarction in a thyroid nodule after fine needle aspiration: report of 2 cases with a discussion of the cause of pitfalls in the histopathologic diagnosis of papillary thyroid carcinoma. 30 Aug 2009
- Galectin-3 cytotest in thyroid follicular neoplasia: a prospective, monoinstitutional study. 30 Aug 2009
- Regulation of expression and secretion of galectin-3 in human monocyte-derived dendritic cells. 19 Aug 2009
- Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface. 16 Aug 2009
- A mechanism for incorporation of galectin-3 into the spliceosome through its association with U1 snRNP. 16 Aug 2009
- Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. 10 Aug 2009
- Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. 30 Jul 2009
- Conformational entropy changes upon lactose binding to the carbohydrate recognition domain of galectin-3. 28 Jul 2009
- Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3. 4 Jul 2009
- The regulation of inflammation by galectin-3. 29 Jun 2009
- Galectin-3 regulates T-cell functions. 29 Jun 2009
- Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. 29 Jun 2009
- Expression of Galectin-3, CD138, p16INK4a, and TTF-1 in mucinous bronchioloalveolar adenocarcinoma after Hodgkin lymphoma. 29 Jun 2009
- Advanced lipoxidation end-products mediate lipid-induced glomerular injury: role of receptor-mediated mechanisms. 29 Jun 2009
- Galectin-3 mediates post-ischemic tissue remodeling. 28 Jun 2009
- Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier. 23 Jun 2009
See a longer list of these articles.
Technical information about 'Galectin 3'
Definition: A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ. It is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, CELL DIFFERENTIATION, and APOPTOSIS.
Registry Number: 0
Descriptor UI: D037502
Alternative terms: Galectin 3; CBP-30; CBP-35; CBP35; Epsilon-Binding Protein; Epsilon Binding Protein; Galectin-3; HL-29; IgE Binding Protein; Binding Protein, IgE; Protein, IgE Binding; IgEBP; L-29 Lectin; L 29 Lectin; L-31; L-34; L30 Lectin; LGALS3; Mac-2 Antigen; Antigen, Mac-2; Mac 2 Antigen; Macrophage-2 Antigen; Antigen, Macrophage-2; Macrophage 2 Antigen; Carbohydrate-Binding Protein 35; Carbohydrate Binding Protein 35;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D12.776.503.307.300;
History Note: 2003; use GALECTIN 3 (NM) 1994-2002