gamma-Aminobutyric Acid - Metabolism
Research News and Information

Saturday, November 21, 2009

The distribution of GAD67-mRNA in the adult zebrafish (teleost) forebrain reveals a prosomeric pattern and suggests previously unidentified homologies to tetrapods.

18 Oct 2009 We used in situ hybridization on sections to examine the distribution of GAD67-expressing cell populations in the entire forebrain of the adult zebrafish. GAD67 is predominantly expressed in the olfactory bulb (OB), all regions of the subpallium ... Read more...

Associative pairing involving monocular stimulation selectively mobilizes a subclass of GABAergic interneurons in the mouse visual cortex.

18 Oct 2009 Levels of gamma-aminobutyric acid (GABA) and its synthesizing enzyme in cerebral cortex are regulated by sensory experience. Previously we found that associative pairing of vibrissae stimulation and tail shock results in upregulation of GABAergic ... Read more...

Extrasynaptic GABAA receptors: form, pharmacology, and function.

12 Oct 2009 GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABA(A) and GABA(B) receptors. Recently, a novel form of GABA(A) receptor-mediated inhibition, termed "tonic" inhibition, has been described. Whereas synaptic GABA(A) ... Read more...

Latest indexed articles for 'gamma-Aminobutyric Acid - Metabolism'

These are the very latest articles for this heading:

• The necessity of NKCC1: loss of the chloride cotransporter in a knock-out model and potential compensatory mechanisms. 19 Oct 2009
• The distribution of GAD67-mRNA in the adult zebrafish (teleost) forebrain reveals a prosomeric pattern and suggests previously unidentified homologies to tetrapods. 18 Oct 2009
• Associative pairing involving monocular stimulation selectively mobilizes a subclass of GABAergic interneurons in the mouse visual cortex. 18 Oct 2009
• Extrasynaptic GABAA receptors: form, pharmacology, and function. 12 Oct 2009
• Quantitative analysis of neurons with Kv3 potassium channel subunits, Kv3.1b and Kv3.2, in macaque primary visual cortex. 29 Sep 2009
• Role of GABA transporter 3 in GABAergic synaptic transmission at striatal output neurons. 29 Sep 2009
• Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. 29 Sep 2009
• GABA uptake-dependent Ca(2+) signaling in developing olfactory bulb astrocytes. 28 Sep 2009
• Bidirectional signaling of ErbB and Eph receptors at synapses. 27 Sep 2009
• Computational sophistication at a single GABAergic connection. 22 Sep 2009
• Discharge profiles of identified GABAergic in comparison to cholinergic and putative glutamatergic basal forebrain neurons across the sleep-wake cycle. 21 Sep 2009
• Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish: cellular organization and neurotransmitters. 18 Sep 2009
• GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses. 14 Sep 2009
• Spontaneous activity in the developing mouse midbrain driven by an external pacemaker. 13 Sep 2009
• Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. 8 Sep 2009
• Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin. 8 Sep 2009
• Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging. 2 Sep 2009
• Lack of kainic acid-induced gamma oscillations predicts subsequent CA1 excitotoxic cell death. 2 Sep 2009
• GABAergic interneurons targeting dendrites of pyramidal cells in the CA1 area of the hippocampus. 2 Sep 2009
• Activation of nicotinic acetylcholine receptors enhances a slow calcium-dependent potassium conductance and reduces the firing of stratum oriens interneurons. 2 Sep 2009

See a longer list of these articles.

Technical information about 'gamma-Aminobutyric Acid'

Definition: The most common inhibitory neurotransmitter in the central nervous system.

Chemical name: Butanoic acid, 4-amino-

Registry Number: 56-12-2

Descriptor UI: D005680

Alternative terms: gamma-Aminobutyric Acid; gamma Aminobutyric Acid; GABA; Aminalon; Aminalone; 4-Aminobutanoic Acid; 4 Aminobutanoic Acid; 4-Aminobutyric Acid; 4 Aminobutyric Acid; gamma-Aminobutyric Acid, Hydrochloride; Acid, Hydrochloride gamma-Aminobutyric; Hydrochloride gamma-Aminobutyric Acid; gamma Aminobutyric Acid, Hydrochloride; Gammalon; gamma-Aminobutyric Acid, Monosodium Salt; gamma Aminobutyric Acid, Monosodium Salt; gamma-Aminobutyric Acid, Zinc Salt (2:1); gamma-Aminobutyric Acid, Calcium Salt (2:1); gamma-Aminobutyric Acid, Monolithium Salt; gamma Aminobutyric Acid, Monolithium Salt; Lithium GABA; GABA, Lithium;

Related Mesh Headings: Receptors, GABA; GABA Agents;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: GABA Agents;

Tree Number: D02.241.081.160.050.350; D12.125.190.350;

History Note: 2001(1975); use AMINOBUTYRIC ACIDS 1966-1974