gamma-Aminobutyric Acid
Research News and Information

Saturday, November 21, 2009

Two classes of GABAergic neurons in the inferior colliculus.

2 Nov 2009 The inferior colliculus (IC) is unique, having both glutamatergic and GABAergic projections ascending to the thalamus. Although subpopulations of GABAergic neurons in the IC have been proposed, criteria to distinguish them have been elusive and ... Read more...

Angelman syndrome: current understanding and research prospects.

30 Oct 2009 Angelman syndrome is a neurogenetic disorder characterized by developmental delay, severe intellectual disability, absent speech, exuberant behavior with happy demeanor, motor impairment, and epilepsy, due to deficient UBE3A gene expression that may ... Read more...

A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.

30 Oct 2009 BACKGROUND: Gabapentin and ketamine are popular analgesic adjuvants for improving perioperative pain management. We designed this double-blind, placebo-controlled study to test and compare the preventive effects of perioperative ketamine and ... Read more...

Latest indexed articles for 'gamma-Aminobutyric Acid'

These are the very latest articles for this heading:

• Two classes of GABAergic neurons in the inferior colliculus. 2 Nov 2009
• Angelman syndrome: current understanding and research prospects. 30 Oct 2009
• A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy. 30 Oct 2009
• Craniotomy pain: trying to do better. 30 Oct 2009
• T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids. 19 Oct 2009
• The necessity of NKCC1: loss of the chloride cotransporter in a knock-out model and potential compensatory mechanisms. 19 Oct 2009
• The distribution of GAD67-mRNA in the adult zebrafish (teleost) forebrain reveals a prosomeric pattern and suggests previously unidentified homologies to tetrapods. 18 Oct 2009
• Associative pairing involving monocular stimulation selectively mobilizes a subclass of GABAergic interneurons in the mouse visual cortex. 18 Oct 2009
• Extrasynaptic GABAA receptors: form, pharmacology, and function. 12 Oct 2009
• Increase of intracellular Ca2+ by P2Y but not P2X receptors in cultured cortical multipolar neurons of the rat. 8 Oct 2009
• Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis. 6 Oct 2009
• Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit. 30 Sep 2009
• An analysis of disease severity based on SMN2 copy number in adults with spinal muscular atrophy. 29 Sep 2009
• Quantitative analysis of neurons with Kv3 potassium channel subunits, Kv3.1b and Kv3.2, in macaque primary visual cortex. 29 Sep 2009
• Role of GABA transporter 3 in GABAergic synaptic transmission at striatal output neurons. 29 Sep 2009
• Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells. 29 Sep 2009
• Pathogenesis of Barrett's esophagus: bile acids inhibit the Notch signaling pathway with induction of CDX2 gene expression in human esophageal cells. 29 Sep 2009
• Treatment of neuropathic pain: an overview of recent guidelines. 29 Sep 2009
• GABA uptake-dependent Ca(2+) signaling in developing olfactory bulb astrocytes. 28 Sep 2009
• Neuropathic pain treatment: a further step forward. 28 Sep 2009

See a longer list of these articles.

Technical information about 'gamma-Aminobutyric Acid'

Definition: The most common inhibitory neurotransmitter in the central nervous system.

Chemical name: Butanoic acid, 4-amino-

Registry Number: 56-12-2

Descriptor UI: D005680

Alternative terms: gamma-Aminobutyric Acid; gamma Aminobutyric Acid; GABA; Aminalon; Aminalone; 4-Aminobutanoic Acid; 4 Aminobutanoic Acid; 4-Aminobutyric Acid; 4 Aminobutyric Acid; gamma-Aminobutyric Acid, Hydrochloride; Acid, Hydrochloride gamma-Aminobutyric; Hydrochloride gamma-Aminobutyric Acid; gamma Aminobutyric Acid, Hydrochloride; Gammalon; gamma-Aminobutyric Acid, Monosodium Salt; gamma Aminobutyric Acid, Monosodium Salt; gamma-Aminobutyric Acid, Zinc Salt (2:1); gamma-Aminobutyric Acid, Calcium Salt (2:1); gamma-Aminobutyric Acid, Monolithium Salt; gamma Aminobutyric Acid, Monolithium Salt; Lithium GABA; GABA, Lithium;

Related Mesh Headings: Receptors, GABA; GABA Agents;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: GABA Agents;

Tree Number: D02.241.081.160.050.350; D12.125.190.350;

History Note: 2001(1975); use AMINOBUTYRIC ACIDS 1966-1974