GATA3 Transcription Factor
Research News and Information

Sunday, November 22, 2009

Expression of the Gata3 transcription factor in the acoustic ganglion of the developing avian inner ear.

18 Oct 2009 During the development of the inner ear, auditory and vestibular ganglion neurons are generated in a highly regulated sequential process. First, neuroblasts are specified, delaminate from the epithelium of the otocyst, and migrate to form the ... Read more...

PU.1 regulates TCR expression by modulating GATA-3 activity.

13 Oct 2009 The Ets transcription factor PU.1 is a master regulator for the development of multiple lineages during hematopoiesis. The expression pattern of PU.1 is dynamically regulated during early T lineage development in the thymus. We previously revealed ... Read more...

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone.

10 Oct 2009 Type I diabetes mellitus is caused by autoimmune destruction of pancreatic beta cells, and effective treatment of the disease might require rescuing beta cell function in a context of reinstalled immune tolerance. Sertoli cells (SCs) are found in ... Read more...

Latest indexed articles for 'GATA3 Transcription Factor'

These are the very latest articles for this heading:

• Expression of the Gata3 transcription factor in the acoustic ganglion of the developing avian inner ear. 18 Oct 2009
• PU.1 regulates TCR expression by modulating GATA-3 activity. 13 Oct 2009
• Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone. 10 Oct 2009
• T cell receptor signaling induced by an analog peptide of type II collagen requires activation of Syk. 29 Sep 2009
• Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation. 26 Sep 2009
• Role of Cybr, a cytohesin binder and regulator, in CD4(+) T-cell function and host immunity. 7 Sep 2009
• GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation in human keratinocytes. 5 Sep 2009
• Gene expression profiling in mice with enforced Gata3 expression reveals putative targets of Gata3 in double positive thymocytes. 31 Aug 2009
• Transcription factor GATA-3 is essential for lens development. 30 Aug 2009
• A missense GATA3 mutation, Thr272Ile, causes the hypoparathyroidism, deafness, and renal dysplasia syndrome. 30 Aug 2009
• Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells. 25 Aug 2009
• GATA factors in human neuroblastoma: distinctive expression patterns in clinical subtypes. 23 Aug 2009
• T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma. 31 Jul 2009
• T(H)2 bias: Mina tips the balance. 30 Jul 2009
• IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. 27 Jul 2009
• Promoter activity 5' of Dbeta2 is coordinated by E47, Runx1, and GATA-3. 7 Jul 2009
• Transcription factor GATA-3 in Atlantic salmon (Salmo salar): molecular characterization, promoter activity and expression analysis. 30 Jun 2009
• HDR (Hypoparathyroidism, Deafness, Renal dysplasia) syndrome associated to GATA3 gene duplication. 29 Jun 2009
• Glycoprotein isolated from Dioscorea batatas Decne modulates expressions of IL-4 and IL-10 in primary-cultured mouse lymphocytes. 29 Jun 2009
• Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression. 27 Jun 2009

See a longer list of these articles.

Technical information about 'GATA3 Transcription Factor'

Definition: A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.

Registry Number: 0

Descriptor UI: D050990

Alternative terms: GATA3 Transcription Factor; Transcription Factor, GATA3; NF-E1C Protein; NF E1C Protein; GATA-3 Factors; GATA 3 Factors; Transcription Factor GATA3; GATA3, Transcription Factor; Nuclear Factor-Erythroid 1C; Nuclear Factor Erythroid 1C;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.235.687; D12.776.260.257.300; D12.776.930.316.687; D12.776.930.321.300;

History Note: 2006(1991)