Gene Deletion
Research News and Information

Saturday, November 21, 2009

Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae.

9 Dec 2009 The Saccharomyces cerevisiae genome encodes a Flo (flocculin) adhesin family responsible for cell-cell and cell-surface adherence. In commonly used laboratory strains, these FLO genes are transcriptionally silent, because of a nonsense mutation in ... Read more...

Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli.

12 Nov 2009 Curli are adhesive fimbriae of Escherichia coli and Salmonella enterica. Expression of curli (csgA) and cellulose (bcsA) is co-activated by the transcriptional activator CsgD. In this study, we investigated the contribution of curli and cellulose to ... Read more...

Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.

2 Nov 2009 Neuroligins are cell adhesion molecules involved in synapse formation and/or function. Neurons express four neuroligins (NL1-NL4), of which NL1 is specific to excitatory and NL2 to inhibitory synapses. Excitatory and inhibitory synapses include ... Read more...

Latest indexed articles for 'Gene Deletion'

These are the very latest articles for this heading:

• Phenotypic diversity of Flo protein family-mediated adhesion in Saccharomyces cerevisiae. 9 Dec 2009
• Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli. 12 Nov 2009
• Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons. 2 Nov 2009
• Array-CGH detection of a de novo 0.7-Mb deletion in 19p13.13 including CACNA1A associated with mental retardation and epilepsy with infantile spasms. 30 Oct 2009
• Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study. 30 Oct 2009
• ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses. 27 Oct 2009
• Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation. 17 Oct 2009
• Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2). 17 Oct 2009
• A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity. 17 Oct 2009
• Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates. 13 Oct 2009
• Toll-like receptors 1 and 2 heterodimers alter Borrelia burgdorferi gene expression in mice and ticks. 13 Oct 2009
• Adenosine triphosphate depletion of erythrocytes simulates the phenotype associated with pyruvate kinase deficiency and confers protection against Plasmodium falciparum in vitro. 13 Oct 2009
• Reduced expression and homozygous deletion of annexin A10 in gastric carcinoma. 13 Oct 2009
• Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene. 11 Oct 2009
• Telomeric circles: universal players in telomere maintenance? 4 Oct 2009
• The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. 3 Oct 2009
• Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes. 3 Oct 2009
• Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. 30 Sep 2009
• Deletion of glycine transporter 1 (GlyT1) in forebrain neurons facilitates reversal learning: enhanced cognitive adaptability? 29 Sep 2009
• Are there any more ovarian tumor suppressor genes? A new perspective using ultra high-resolution copy number and loss of heterozygosity analysis. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Gene Deletion'

Definition: A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.

Descriptor UI: D017353

Alternative terms: Gene Deletion; Deletion, Gene; Deletions, Gene; Gene Deletions;

Tree Number: G05.355.600.800.320; G05.365.590.762.320;

Online Note: use CHROMOSOME DELETION to search GENE DELETION 1984-92

History Note: 93; was see CHROMOSOME DELETION 1984-92