Gene Expression Regulation, Developmental - Drug effects
Research News and Information

Sunday, November 22, 2009

Transcriptional profiling of the hormone-responsive stages of spermatogenesis reveals cell-, stage-, and hormone-specific events.

29 Sep 2009 Spermatogenesis occurs within the highly complex seminiferous epithelium. This cyclic process is accompanied by dynamic stage-specific transcriptional changes and is driven by androgens and FSH by mechanisms that are unclear. Here we report the ... Read more...

DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.

22 Sep 2009 Disrupted-in-schizophrenia 1 (DISC1), a susceptibility gene for major mental illnesses, regulates multiple aspects of embryonic and adult neurogenesis. Here, we show that DISC1 suppression in newborn neurons of the adult hippocampus leads to ... Read more...

The impact of human superoxide dismutase 1 expression in a mouse model on the embryotoxicity of hydroxyurea.

30 Aug 2009 BACKGROUND: Oxidative stress is hypothesized to mediate embryotoxicity during organogenesis, yet the reactive oxygen species involved are not defined. The superoxide oxygen radical is converted to hydrogen peroxide, a less reactive species, by ... Read more...

Latest indexed articles for 'Gene Expression Regulation, Developmental - Drug effects'

These are the very latest articles for this heading:

• Transcriptional profiling of the hormone-responsive stages of spermatogenesis reveals cell-, stage-, and hormone-specific events. 29 Sep 2009
• DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. 22 Sep 2009
• The impact of human superoxide dismutase 1 expression in a mouse model on the embryotoxicity of hydroxyurea. 30 Aug 2009
• Smad2/3 is involved in growth inhibition of mouse embryonic palate mesenchymal cells induced by all-trans retinoic acid. 30 Aug 2009
• [Influence of Tripterygium wilfordii on the expression of spermiogenesis related genes Herc4, Ipo11 and Mrto4 in mice] 30 Aug 2009
• Involvement of polyadenylation status on maternal gene expression during in vitro maturation of porcine oocytes. 30 Aug 2009
• Early zygotic expression of transcription factors and signal molecules in fully dissociated embryonic cells of Ciona intestinalis: A microarray analysis. 30 Aug 2009
• Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. 25 Aug 2009
• Epigenetic transgenerational effects of endocrine disruptors on male reproduction. 24 Aug 2009
• Dynamic Pax6 expression during the neurogenic cell cycle influences proliferation and cell fate choices of retinal progenitors. 15 Aug 2009
• Expression of the genes siamois, engrailed-2, bmp4 and myf5 during Xenopus development in presence of the marine toxins okadaic acid and palytoxin. 12 Aug 2009
• Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats. 30 Jul 2009
• Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stability in vivo. 30 Jul 2009
• Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model. 30 Jul 2009
• Phenoloxidase activation in the embryo of the common cuttlefish Sepia officinalis and responses to the Ag and Cu exposure. 15 Jul 2009
• The ankyrin repeat gene family in rice: genome-wide identification, classification and expression profiling. 14 Jul 2009
• Monoisoamyl dimercaptosuccinic acid abrogates arsenic-induced developmental toxicity in human embryonic stem cell-derived embryoid bodies: comparison with in vivo studies. 13 Jul 2009
• The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish. 13 Jul 2009
• Characterization of vtg-1 mRNA expression during ontogeny in Oreochromis mossambicus (PETERS). 13 Jul 2009
• Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. 3 Jul 2009

See a longer list of these articles.

Technical information about 'Gene Expression Regulation, Developmental'

Definition: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.

Descriptor UI: D018507

Alternative terms: Gene Expression Regulation, Developmental; Developmental Gene Expression Regulation; Regulation of Gene Expression, Developmental; Gene Expression Regulation, Embryologic; Regulation, Gene Expression, Embryologic; Embryologic Gene Expression Regulation; Regulation of Gene Expression, Embryologic; Regulation, Gene Expression, Developmental;

Related Mesh Headings: Genes, Developmental;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.355.315.310;

History Note: 95

Technical Notes: developmental includes embryonic; DF: GENE EXPRESSION REG DEVELOPMENTAL