Gene Rearrangement - Genetics
Research News and Information

Sunday, November 22, 2009

On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

23 Jun 2009 Transcription in eukaryotic genomes depends on enzymes that regulate the degree of histone H3 lysine 4 (H3K4) methylation. The mixed lineage leukemia protein-1 (MLL1) is a member of the SET1 family of H3K4 methyltransferases and is frequently ... Read more...

GR-Aligner: an algorithm for aligning pairwise genomic sequences containing rearrangement events.

17 Jun 2009 MOTIVATION: Homologous genomic sequences between species usually contain different rearrangement events. Whether some specific patterns existed in the breakpoint regions that caused such events to occur is still unclear. To resolve this question, it ... Read more...

Genomic copy number variation, human health, and disease.

13 Jun 2009 Despite the long recognised effects of chromosomal structural abnormalities and completion of the Human Genome Project, much of the structural variation in the genome has gone unrecognised until recently. Deletions and duplications of DNA strands of ... Read more...

Latest indexed articles for 'Gene Rearrangement - Genetics'

These are the very latest articles for this heading:

• Array-CGH detection of a de novo 0.7-Mb deletion in 19p13.13 including CACNA1A associated with mental retardation and epilepsy with infantile spasms. 30 Oct 2009
• On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex. 23 Jun 2009
• GR-Aligner: an algorithm for aligning pairwise genomic sequences containing rearrangement events. 17 Jun 2009
• Genomic copy number variation, human health, and disease. 13 Jun 2009
• Cryptic genomic imbalances in de novo and inherited apparently balanced chromosomal rearrangements: array CGH study of 47 unrelated cases. 4 Jun 2009
• Diagnosis of intraocular lymphoma by polymerase chain reaction analysis and cytokine profiling of the vitreous fluid. 29 May 2009
• Chromosomal rearrangements between serotype A and D strains in Cryptococcus neoformans. 11 May 2009
• Unusual histological variant of Ewing's sarcoma of mandible. 30 Apr 2009
• Too many ends: aberrant transposition. 29 Apr 2009
• Simultaneous occurrence of MLL and RARA rearrangements in a pediatric acute lymphoblastic leukemia patient. 29 Apr 2009
• Myeloproliferative disorder with eosinophilia and ETV6-ABL gene rearrangement: efficacy of second-generation tyrosine kinase inhibitors. 23 Apr 2009
• [Soft tissue tumors in neonates] 21 Apr 2009
• Cross-species chromosome painting in Cetartiodactyla: reconstructing the karyotype evolution in key phylogenetic lineages. 5 Apr 2009
• Genome halving with double cut and join. 30 Mar 2009
• Clear cell sarcoma of the temporal region: case report, review of the literature, and genetic analysis. 30 Mar 2009
• Ewing's sarcoma / primitive neuroectodermal tumor of the kidney. 15 Mar 2009
• Chromosomal rearrangements underlying karyotype differences between Chinese pangolin (Manis pentadactyla) and Malayan pangolin (Manis javanica) revealed by chromosome painting. 11 Mar 2009
• Carcinomas of the upper aerodigestive tract with rearrangement of the nuclear protein of the testis (NUT) gene (NUT midline carcinomas). 27 Feb 2009
• The unusual way to make a genetically active nucleus. 30 Jan 2009
• Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation. 4 Jan 2009

See a longer list of these articles.

Technical information about 'Gene Rearrangement'

Definition: The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development.

Descriptor UI: D015321

Alternative terms: Gene Rearrangement; Gene Rearrangements; Rearrangement, Gene; Rearrangements, Gene; DNA Rearrangement; DNA Rearrangements; Rearrangement, DNA; Rearrangements, DNA;

Related Mesh Headings: Antibody Diversity; Genes, Immunoglobulin; Immunoglobulin Variable Region; Translocation, Genetic; VDJ Recombinases;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.355.330;

History Note: 89

Technical Notes: DF: GENE REARR