Gene Transfer Techniques
Research News and Information

Monday, November 23, 2009

Periodontal gene transfer by ultrasound and nano/microbubbles.

30 Oct 2009 A non-viral gene delivery approach with nano/microbubbles and ultrasound offers opportunities for targeting soft tissues for gene therapy. The periodontium is a complex structure comprised of hard (cementum, alveolar bone) and soft tissues ... Read more...

Comparison of gene delivery techniques for therapeutic angiogenesis ultrasound-mediated destruction of carrier microbubbles versus direct intramuscular injection.

25 Oct 2009 OBJECTIVES: This study was designed to compare the efficacy of angiogenic gene delivery by ultrasound-mediated (UM) destruction of intravenous carrier microbubbles to direct intramuscular (IM) injections. BACKGROUND: Current trials of gene therapy ... Read more...

Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression.

18 Oct 2009 Viruses have substantial value as vehicles for transporting transgenes into neurons. Each virus has its own set of attributes for addressing neuroscience-related questions. Here we review some of the advantages and limitations of herpes, ... Read more...

Latest indexed articles for 'Gene Transfer Techniques'

These are the very latest articles for this heading:

• Periodontal gene transfer by ultrasound and nano/microbubbles. 30 Oct 2009
• Comparison of gene delivery techniques for therapeutic angiogenesis ultrasound-mediated destruction of carrier microbubbles versus direct intramuscular injection. 25 Oct 2009
• Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression. 18 Oct 2009
• Opening up the JCN toolbox. 18 Oct 2009
• Transposon-mediated BAC transgenesis in zebrafish and mice. 14 Oct 2009
• T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event. 6 Oct 2009
• Absence of thrombospondin-2 causes age-related dilated cardiomyopathy. 3 Oct 2009
• Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. 3 Oct 2009
• Gateway to the diseased brain. 29 Sep 2009
• Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles. 29 Sep 2009
• Direct selection for ribozyme cleavage activity in cells. 21 Sep 2009
• Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. 15 Sep 2009
• Isolation and genetic manipulation of adult cardiac myocytes for confocal imaging. 15 Sep 2009
• Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway. 12 Sep 2009
• The use of viral gene transfer in studies of brainstem noradrenergic and serotonergic neurons. 10 Sep 2009
• Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery. 6 Sep 2009
• Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. 4 Sep 2009
• An efficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cells. 2 Sep 2009
• Zebrafish enhancer detection (ZED) vector: a new tool to facilitate transgenesis and the functional analysis of cis-regulatory regions in zebrafish. 30 Aug 2009
• Reducible disulfide-based non-viral gene delivery systems. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Gene Transfer Techniques'

Definition: The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene transfer such as cell hybridization, LIPOSOMES or microcell-mediated gene transfer, ELECTROPORATION, chromosome-mediated gene transfer, TRANSFECTION, and GENETIC TRANSDUCTION. Gene transfer may result in genetically transformed cells and individual organisms.

Descriptor UI: D018014

Alternative terms: Gene Transfer Techniques; Technique, Gene Transfer; Techniques, Gene Transfer; Transfer Technique, Gene; Transfer Techniques, Gene; Transgenesis; Gene Transfer Technique; Gene Delivery Systems; Delivery System, Gene; Delivery Systems, Gene; Gene Delivery System;

Related Mesh Headings: Gene Therapy;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E05.393.350;

History Note: 2001(1994); use TRANSFECTION 1988-93

Technical Notes: note category: do not confuse with GENE TRANSFER, HORIZONTAL