Generalization, Stimulus - Drug effects
Research News and Information

Sunday, November 22, 2009

Reduced sensitivity to the locomotor-stimulant effects of cocaine is associated with increased sensitivity to its discriminative stimulus properties.

30 Jan 2009 Outbred Long-Evans rats exhibit wide variation in their locomotor response to cocaine. Here, we investigated the relationship between these individual differences and interoceptive effects of cocaine in low cocaine responder (LCR) and high cocaine ... Read more...

Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats.

7 Sep 2008 The nicotinic partial agonist varenicline (VCL) is a recently approved medication for the treatment of tobacco dependence, yet very little preclinical research on this drug has been published. The present experiment examined the nicotinic partial ... Read more...

Effect of 8-hydroxy-2-(N,N-di-n-propylamino)tetralin and MDMA on the discriminative stimulus effects of the classical hallucinogen DOM in rats.

15 Aug 2008 Co-administration of the 5-HT1A serotonin receptor agonist (+/-)8-hydroxy-2-(N,N-di-n-propylamino)tetralin [(+/-)8-OH DPAT] enhances the discriminative stimulus effects of the classical hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane ... Read more...

Latest indexed articles for 'Generalization, Stimulus - Drug effects'

These are the very latest articles for this heading:

• Reduced sensitivity to the locomotor-stimulant effects of cocaine is associated with increased sensitivity to its discriminative stimulus properties. 30 Jan 2009
• Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats. 7 Sep 2008
• Effect of 8-hydroxy-2-(N,N-di-n-propylamino)tetralin and MDMA on the discriminative stimulus effects of the classical hallucinogen DOM in rats. 15 Aug 2008
• Constructing quality profiles for taste compounds in rats: a novel paradigm. 7 Jul 2008
• The role of comparison in perceptual learning: effects of concurrent exposure to similar stimuli on the perceptual effectiveness of their unique features. 29 Apr 2008
• Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats. 7 Feb 2008
• The conditional stimulus effects of nicotine vary as a function of training dose. 29 Nov 2007
• Participation of the dorsal hippocampus in stimulus discrimination with scopolamine. 7 Aug 2007
• Psilocybin-induced stimulus control in the rat. 20 Jun 2007
• The 5-HT3 receptor partial agonist MD-354 (meta-chlorophenylguanidine) enhances the discriminative stimulus actions of (+)amphetamine in rats. 28 Mar 2007
• Cycloheximide: no ordinary bitter stimulus. 21 Feb 2007
• Behavioral and neuropharmacological characterization of nicotine as a conditional stimulus. 30 Jan 2007
• Effects of D-cycloserine on extinction of learned fear to an olfactory cue. 30 Jan 2007
• alpha-Ethyltryptamine (alpha-ET) as a discriminative stimulus in rats. 14 Nov 2006
• Reinforcement schedule effects in rats trained to discriminate 3,4-methylenedioxymethamphetamine (MDMA) or cocaine. 21 Sep 2006
• Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle. 27 Feb 2006
• Generalization to atypical antipsychotic drugs depends on training dose in rats trained to discriminate 1.25 mg/kg clozapine versus 5.0 mg/kg clozapine versus vehicle in a three-choice drug discrimination task. 30 Oct 2005
• Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats. 10 Oct 2005
• Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats. 10 Oct 2005
• Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey: a further characterization. 18 Apr 2005

See a longer list of these articles.

Technical information about 'Generalization, Stimulus'

Definition: The tendency to react to stimuli that are different from, but somewhat similar to, the stimulus used as a conditioned stimulus.

Descriptor UI: D005795

Alternative terms: Generalization, Stimulus; Generalizations, Stimulus; Stimulus Generalization; Stimulus Generalizations;

Allowable Qualifiers: classification; drug effects; physiology; radiation effects; ethics;

Tree Number: F02.463.425.357.526;

History Note: 69(65)