Genetic Predisposition to Disease - Genetics
Research News and Information

Saturday, November 21, 2009

Genetic complexity of absence seizures in substrains of C3H mice.

15 Dec 2009 Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly understood because of genetic and phenotypic heterogeneity. The inbred mouse strain C3H/He exhibits spontaneous absence seizures characterized by spike and ... Read more...

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations.

30 Oct 2009 CONTEXT: The 5-HTTLPR polymorphism in the promoter region of the serotonin transporter gene (SLC6A4) has been found to moderate several categories of emotional response after stressful life events. Previous studies generally focused on its effect on ... Read more...

Influence of genetic background on fluoride metabolism in mice.

30 Oct 2009 A/J and 129P3/J mouse strains have different susceptibilities to dental fluorosis, due to their genetic backgrounds. This study tested whether these differences are due to variations in water intake and/or F metabolism. A/J (susceptible to dental ... Read more...

Latest indexed articles for 'Genetic Predisposition to Disease - Genetics'

These are the very latest articles for this heading:

• Genetic complexity of absence seizures in substrains of C3H mice. 15 Dec 2009
• Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. 30 Oct 2009
• Influence of genetic background on fluoride metabolism in mice. 30 Oct 2009
• Clinical and genetic factors predictive of mortality in early systemic sclerosis. 13 Oct 2009
• A genome-wide linkage and association scan reveals novel loci for autism. 6 Oct 2009
• Finding the missing heritability of complex diseases. 6 Oct 2009
• Human genetics: Sharp focus on the variable genome. 6 Oct 2009
• An agenda for personalized medicine. 6 Oct 2009
• Human genetics: Hit or miss? 6 Oct 2009
• Putting DNA to the test. 6 Oct 2009
• A common haplotype of the LBP gene predisposes to severe sepsis. 29 Sep 2009
• Is it time for intensivists to learn genomics? 29 Sep 2009
• Gene copy number: learning to count past two. 29 Sep 2009
• CCL3L1 and HIV/AIDS susceptibility. 29 Sep 2009
• Clinical and genetic profile of Avellino corneal dystrophy in 2 families from north India. 29 Sep 2009
• Association of functional gene polymorphism IL-1beta in patients with external apical root resorption. 29 Sep 2009
• [Estimation of individual breast cancer risk: relevance and limits of risk estimation models] 29 Sep 2009
• A novel nonsynonymous variant of matrix metalloproteinase-7 confers risk of liver cirrhosis. 29 Sep 2009
• A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C. 29 Sep 2009
• Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Genetic Predisposition to Disease'

Definition: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.

Descriptor UI: D020022

Alternative terms: Genetic Predisposition to Disease; Predisposition, Genetic; Genetic Predispositions; Predispositions, Genetic; Susceptibility, Genetic; Genetic Susceptibilities; Susceptibilities, Genetic; Genetic Susceptibility; Genetic Predisposition;

Related Mesh Headings: Genetic Screening;

Allowable Qualifiers: classification; ethnology; embryology; epidemiology; etiology; genetics; history; prevention & control; psychology;

Tree Number: C23.550.291.687.500; G05.380.355;

History Note: 99

Technical Notes: latent susceptibility to dis only: coord with specific dis/genet; for positive genetic predisposition (like longevity) use specific trait/genet