Genetic Predisposition to Disease
Research News and Information

Sunday, November 08, 2009

Genetic complexity of absence seizures in substrains of C3H mice.

15 Dec 2009 Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly understood because of genetic and phenotypic heterogeneity. The inbred mouse strain C3H/He exhibits spontaneous absence seizures characterized by spike and ... Read more...

Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?

5 Dec 2009 Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of research in which a number of key technologies converge: in ... Read more...

Fanconi anemia and biallelic BRCA2 mutation diagnosed in a young child with an embryonal CNS tumor.

29 Nov 2009 Medulloblastoma, the most common pediatric malignant brain tumor often arises sporadically; however, in a subgroup of patients, there exist familial conditions such as Fanconi anemia with biallelic BRCA2 mutation that predispose patients to ... Read more...

Latest indexed articles for 'Genetic Predisposition to Disease'

These are the very latest articles for this heading:

• Genetic complexity of absence seizures in substrains of C3H mice. 15 Dec 2009
• Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes? 5 Dec 2009
• Fanconi anemia and biallelic BRCA2 mutation diagnosed in a young child with an embryonal CNS tumor. 29 Nov 2009
• Genetic deficiencies of innate immune signalling in human infectious disease. 30 Oct 2009
• Anesthesia and pharmacogenomics: not ready for prime time. 30 Oct 2009
• Association of polymorphisms in regulatory regions of interleukin-12p40 gene and cytokine serum level with colorectal cancer. 30 Oct 2009
• Influence of genetic background on fluoride metabolism in mice. 30 Oct 2009
• CDK4 IVS4-nt40G-->A and T2D-associated obesity in Italians. 30 Oct 2009
• Yeast infections--human genetics on the rise. 27 Oct 2009
• Human dectin-1 deficiency and mucocutaneous fungal infections. 27 Oct 2009
• A homozygous CARD9 mutation in a family with susceptibility to fungal infections. 27 Oct 2009
• Association of APOE polymorphism with chronic kidney disease in a nationally representative sample: a Third National Health and Nutrition Examination Survey (NHANES III) Genetic Study. 21 Oct 2009
• Suggestive linkage detected for blood pressure related traits on 2q and 22q in the population on the Samoan islands. 21 Oct 2009
• [Genetics in chronic obstructive pulmonary disease] 20 Oct 2009
• Implications of hypertrophic cardiomyopathy transmitted by sperm donation. 19 Oct 2009
• Cardiovascular diseases and risk of hip fracture. 19 Oct 2009
• Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization. 18 Oct 2009
• Viral infection leading to brain dysfunction: more prevalent than appreciated? 13 Oct 2009
• Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03). 13 Oct 2009
• Heritable factors play a major role in determining host responses to Wuchereria bancrofti infection in an isolated South Pacific island population. 13 Oct 2009

See a longer list of these articles.

Technical information about 'Genetic Predisposition to Disease'

Definition: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.

Descriptor UI: D020022

Alternative terms: Genetic Predisposition to Disease; Predisposition, Genetic; Genetic Predispositions; Predispositions, Genetic; Susceptibility, Genetic; Genetic Susceptibilities; Susceptibilities, Genetic; Genetic Susceptibility; Genetic Predisposition;

Related Mesh Headings: Genetic Screening;

Allowable Qualifiers: classification; ethnology; embryology; epidemiology; etiology; genetics; history; prevention & control; psychology;

Tree Number: C23.550.291.687.500; G05.380.355;

History Note: 99

Technical Notes: latent susceptibility to dis only: coord with specific dis/genet; for positive genetic predisposition (like longevity) use specific trait/genet