 |
Genomic Imprinting - Physiology
Research News and Information
Definition of 'Genomic Imprinting'The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992) Common names: Genomic Imprinting; Imprinting, Genomic; Parental Imprinting; Imprinting, Parental; Imprinting, Genetic; Genetic Imprinting |
Sunday, November 22, 2009
The function of non-coding RNAs in genomic imprinting.
30 May 2009 
Non-coding RNAs (ncRNAs) that regulate gene expression in cis or in trans are a shared feature of prokaryotic and eukaryotic genomes. In mammals, cis-acting functions are associated with macro ncRNAs, which can be several hundred thousand ... Read more...
27 Feb 2009 Our previous allelotyping studies of 59 sporadic colorectal cancers revealed that loss of heterozygosity is most frequent for regions of chromosomes 14 and 18. Yet subsequent BAC microarray comparative genomic hybridization studies of the same tumor ... Read more...
ATR, BRCA1 and gammaH2AX localize to unsynapsed chromosomes at the pachytene stage in human oocytes.
30 Dec 2008 Asynapsis of homologous chromosomes at the pachytene stage has been associated with gametogenic failure and infertility, but the cellular mechanisms involved are currently unknown in human meiocytes. In mice, the protein encoded by the breast-cancer ... Read more...
Latest indexed articles for 'Genomic Imprinting - Physiology'
These are the very latest articles for this heading:
- The function of non-coding RNAs in genomic imprinting. 30 May 2009
- Uniparentalism in sporadic colorectal cancer is independent of imprint status, and coordinate for chromosomes 14 and 18. 27 Feb 2009
- ATR, BRCA1 and gammaH2AX localize to unsynapsed chromosomes at the pachytene stage in human oocytes. 30 Dec 2008
- Heritable imprinting defect caused by epigenetic abnormalities in mouse spermatogonial stem cells. 17 Nov 2008
- Patterns of hybrid loss of imprinting reveal tissue- and cluster-specific regulation.
27 Oct 2008 - Impact of genetic and epigenetic factors from early life to later disease. 29 Sep 2008
- Prenatal imprinting of postnatal specific appetites and feeding behavior. 29 Sep 2008
- DNA methyltransferase 1o functions during preimplantation development to preclude a profound level of epigenetic variation. 23 Sep 2008
- Genomic imprinting in the development and evolution of psychotic spectrum conditions. 7 Sep 2008
- PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse. 20 Aug 2008
- [Expression of imprinted Igf2 and Peg1/Mest genes in postimplantation parthenogenetic mouse embryos treated with transforming growth factor alpha in vitro] 30 Jul 2008
- Interview with Rudolf Jaenisch, M.D.
30 Jul 2008 - Physiological dysfunctions associated with mutations of the imprinted Gnas locus. 30 Jul 2008
- A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate. 30 Jul 2008
- Chromatin loops in gene regulation. 13 Jul 2008
- Hybrid vigor and transgenerational epigenetic effects on early mouse embryo phenotype. 16 Jun 2008
- Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis. 13 Jun 2008
- Genomic matrix attachment region and chromosome conformation capture quantitative real time PCR assays identify novel putative regulatory elements at the imprinted Dlk1/Gtl2 locus. 3 May 2008
- Random monoallelic expression: making a choice. 27 Apr 2008
- Nest of origin predicts adult neuron addition rates in the vocal control system of the zebra finch. 19 Apr 2008
See a longer list of these articles.
Technical information about 'Genomic Imprinting'
Definition: The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)
Descriptor UI: D018392
Alternative terms: Genomic Imprinting; Imprinting, Genomic; Parental Imprinting; Imprinting, Parental; Imprinting, Genetic; Genetic Imprinting;
Related Mesh Headings: DNA Methylation;
Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;
Tree Number: G05.355.315.203.500;
History Note: 95