Genomic Imprinting
Research News and Information

Sunday, November 22, 2009

Genomic imprinting: employing and avoiding epigenetic processes.

13 Sep 2009 Genomic imprinting refers to an epigenetic mark that distinguishes parental alleles and results in a monoallelic, parental-specific expression pattern in mammals. Few phenomena in nature depend more on epigenetic mechanisms while at the same time ... Read more...

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints.

31 Aug 2009 Differential DNA methylation of the paternal and maternal alleles regulates the parental origin-specific expression of imprinted genes in mammals. The methylation imprints are established in male and female germ cells during gametogenesis, and the ... Read more...

A grandparent-influenced locus for alcohol preference on mouse chromosome 2.

30 Aug 2009 OBJECTIVE: Loci on mouse chromosome 2 have previously been associated with ethanol consumption. Here, we used a limited access choice paradigm in which mice consume large quantities of ethanol (2-3 g/kg/2 h) with a high preference (>80%). In ... Read more...

Latest indexed articles for 'Genomic Imprinting'

These are the very latest articles for this heading:

• Epigenetics: Ready for the marks. 15 Sep 2009
• Genomic imprinting: employing and avoiding epigenetic processes. 13 Sep 2009
• KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. 31 Aug 2009
• A grandparent-influenced locus for alcohol preference on mouse chromosome 2. 30 Aug 2009
• Imprinting disorders and assisted reproductive technology. 24 Aug 2009
• Assisted reproductive technology, epigenetics, and long-term health: a developmental time bomb still ticking. 24 Aug 2009
• Developmental origins of health and disease: environmental exposures. 24 Aug 2009
• Animal models of epigenetic inheritance. 24 Aug 2009
• Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms. 24 Aug 2009
• Epigenetics: definition, mechanisms and clinical perspective. 24 Aug 2009
• [Epigenetics-related diseases and analytic methods] 30 Jul 2009
• Spermatozoal RNAs: what about their functions? 30 Jul 2009
• Epigenetics in the placenta. 30 Jul 2009
• Maternal imprinting during mouse oocyte growth in vivo and in vitro. 28 Jul 2009
• Detection of differentially expressed genes between Erhualian and Large White placentas on day 75 and 90 of gestation. 24 Jul 2009
• Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia. 29 Jun 2009
• Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation. 29 Jun 2009
• Insulin-like growth factor-II methylation status in lymphocyte DNA and colon cancer risk in the Northern Sweden Health and Disease cohort. 21 Jun 2009
• A randomly integrated transgenic H19 imprinting control region acquires methylation imprinting independently of its establishment in germ cells. 20 Jun 2009
• Genetic dissection of complex endosperm traits. 19 Jun 2009

See a longer list of these articles.

Technical information about 'Genomic Imprinting'

Definition: The variable phenotypic expression of a GENE depending on whether it is of paternal or maternal origin, which is a function of the DNA METHYLATION pattern. Imprinted regions are observed to be more methylated and less transcriptionally active. (Segen, Dictionary of Modern Medicine, 1992)

Descriptor UI: D018392

Alternative terms: Genomic Imprinting; Imprinting, Genomic; Parental Imprinting; Imprinting, Parental; Imprinting, Genetic; Genetic Imprinting;

Related Mesh Headings: DNA Methylation;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.355.315.203.500;

History Note: 95