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Giant Cell Arteritis - Diagnosis
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Definition of 'Giant Cell Arteritis'

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)

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Sunday, November 22, 2009

Giant cell arteritis.

5 Jul 2009 Giant cell arteritis (GCA) is an immune-mediated vasculitis affecting individuals over 50 years of age. It is characterised by granulomatous inflammation that affects medium-sized and large arteries. The wide spectrum of clinical manifestations can ... Read more...


Takayasu arteritis and giant cell arteritis: a spectrum within the same disease?

29 Jun 2009 Giant cell arteritis (GCA) and Takayasu arteritis (TAK) have been considered distinct disorders based on their clinical features, age of onset, and ethnic distribution. However, on closer examination, these disorders appear more similar than ... Read more...


Strokes at time of disease diagnosis in a series of 287 patients with biopsy-proven giant cell arteritis.

29 Jun 2009 Patients with giant cell arteritis (GCA) generally present with cranial ischemic manifestations that are directly related to vascular involvement. They may also experience strokes in the territory of the carotid or the vertebrobasilar artery. We ... Read more...

 

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Technical information about 'Giant Cell Arteritis'

Definition: A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)

Descriptor UI: D013700

Alternative terms: Giant Cell Arteritis; Arteritides, Giant Cell; Arteritis, Giant Cell; Giant Cell Arteritides; Horton Giant Cell Arteritis; Arteritis, Giant Cell, Horton's; Giant Cell Arteritis, Horton; Horton's Disease; Hortons Disease; Horton's Giant Cell Arteritis; Horton Disease; Arteritis, Giant Cell, Horton; Cranial Arteritis; Arteritides, Cranial; Arteritis, Cranial; Cranial Arteritides; Temporal Arteritis; Arteritides, Temporal; Temporal Arteritides; Arteritis, Temporal; Aortic Arteritis, Giant Cell; Giant Cell Aortitis; Giant Cell Aortic Arteritis; Giant Cell Aortitis, Horton's; Aortitis, Giant Cell; Aortitides, Giant Cell; Giant Cell Aortitides; Juvenile Temporal Arteritis; Arteritides, Juvenile Temporal; Arteritis, Juvenile Temporal; Juvenile Temporal Arteritides; Temporal Arteritides, Juvenile; Temporal Arteritis, Juvenile;

Related Mesh Headings: Polymyalgia Rheumatica;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.114.875.700; C10.228.140.300.850.500; C14.907.184.438; C14.907.253.946.700; C14.907.940.090.530; C14.907.940.907.700; C17.800.862.252; C20.111.258.962.800;

History Note: 2008 (1963)

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