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Giant Cell Arteritis - Pathology
Research News and Information
Definition of 'Giant Cell Arteritis'A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed) |
Monday, November 23, 2009
4 Oct 2009
BACKGROUND: Colour Doppler sonography (CDS) is an established technique in the diagnosis of giant-cell (temporal) arteritis (GCA). The predictive value of its diagnostic criteria for GCA (halo sign or stenosis) is related to the pretest probability ... Read more...
Isolated superficial temporal artery dissection masquerading as giant cell arteritis.
30 Aug 2009
A 79-year-old male presented with symptoms suggesting giant cell arteritis (GCA) and elevation of acute-phase reactants. Bilateral superficial temporal artery (STA) biopsies were negative for GCA. However, the right-sided biopsy showed a STA ... Read more...
Jul 2009
Giant cell arteritis (GCA) is a systemic vasculitis associated with severe complications such as loss of vision and, rarely, scalp necrosis. We present a patient with GCA who had bilateral scalp necrosis and an erythrocyte sedimentation rate of only ... Read more...
Latest indexed articles for 'Giant Cell Arteritis - Pathology'
These are the very latest articles for this heading:
- [Value of colour Doppler ultrasonography in relation to clinical pretest probability in giant cell (temporal) arteritis]
4 Oct 2009 - Case of the missed opportunity for temporal artery biopsy.
29 Sep 2009 - Isolated superficial temporal artery dissection masquerading as giant cell arteritis.
30 Aug 2009 - Scalp necrosis in giant cell arteritis: case report and review of the relevance of this cutaneous sign of large-vessel vasculitis.
Jul 2009 - Takayasu arteritis and giant cell arteritis: a spectrum within the same disease?
29 Jun 2009 - Strokes at time of disease diagnosis in a series of 287 patients with biopsy-proven giant cell arteritis.
29 Jun 2009 - Association between toll-like receptor 4 gene polymorphism and biopsy-proven giant cell arteritis.
14 Jun 2009 - Treatment and outcomes of large vessel arteritis.
30 May 2009 - The spectrum of vascular involvement in giant-cell arteritis: clinical consequences of detrimental vascular remodelling at different sites.
30 May 2009 - Temporal arteritis 50 years on.
30 May 2009 - Giant cell arteritis and angiogenesis: a review.
29 Apr 2009 - Long-term follow-up of aortic involvement in giant cell arteritis: a series of 48 patients.
29 Apr 2009 - [Thoracic aortic aneurysm due to giant cell arteritis without any specific symptom]
30 Mar 2009 - Lack of association between STAT4 gene polymorphism and biopsy-proven giant cell arteritis.
28 Mar 2009 - Bilateral brachial neuropathy and acute aortic dissection due to giant cell arteritis.
12 Mar 2009 - [Necrosis of a hairy scalp as a first sign of arteritis temporalis]
12 Mar 2009 - [Imaging techniques for giant cell arteritis. Ultrasound and MRI]
27 Feb 2009 - Expression of the class I interferon-related MxA protein in temporal arteries in polymyalgia rheumatica and temporal arteritis.
27 Feb 2009 - Giant cell arteritis: dendritic cells take two T's to tango.
25 Feb 2009 - Involvement of the ophthalmic artery in giant cell arteritis visualized by 3T MRI.
18 Feb 2009
See a longer list of these articles.
Technical information about 'Giant Cell Arteritis'
Definition: A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
Descriptor UI: D013700
Alternative terms: Giant Cell Arteritis; Arteritides, Giant Cell; Arteritis, Giant Cell; Giant Cell Arteritides; Horton Giant Cell Arteritis; Arteritis, Giant Cell, Horton's; Giant Cell Arteritis, Horton; Horton's Disease; Hortons Disease; Horton's Giant Cell Arteritis; Horton Disease; Arteritis, Giant Cell, Horton; Cranial Arteritis; Arteritides, Cranial; Arteritis, Cranial; Cranial Arteritides; Temporal Arteritis; Arteritides, Temporal; Temporal Arteritides; Arteritis, Temporal; Aortic Arteritis, Giant Cell; Giant Cell Aortitis; Giant Cell Aortic Arteritis; Giant Cell Aortitis, Horton's; Aortitis, Giant Cell; Aortitides, Giant Cell; Giant Cell Aortitides; Juvenile Temporal Arteritis; Arteritides, Juvenile Temporal; Arteritis, Juvenile Temporal; Juvenile Temporal Arteritides; Temporal Arteritides, Juvenile; Temporal Arteritis, Juvenile;
Related Mesh Headings: Polymyalgia Rheumatica;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.114.875.700; C10.228.140.300.850.500; C14.907.184.438; C14.907.253.946.700; C14.907.940.090.530; C14.907.940.907.700; C17.800.862.252; C20.111.258.962.800;
History Note: 2008 (1963)