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Giant Cell Arteritis - Pathology
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Definition of 'Giant Cell Arteritis'

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)

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Monday, November 23, 2009

[Value of colour Doppler ultrasonography in relation to clinical pretest probability in giant cell (temporal) arteritis]

4 Oct 2009 BACKGROUND: Colour Doppler sonography (CDS) is an established technique in the diagnosis of giant-cell (temporal) arteritis (GCA). The predictive value of its diagnostic criteria for GCA (halo sign or stenosis) is related to the pretest probability ... Read more...


Isolated superficial temporal artery dissection masquerading as giant cell arteritis.

30 Aug 2009 A 79-year-old male presented with symptoms suggesting giant cell arteritis (GCA) and elevation of acute-phase reactants. Bilateral superficial temporal artery (STA) biopsies were negative for GCA. However, the right-sided biopsy showed a STA ... Read more...


Scalp necrosis in giant cell arteritis: case report and review of the relevance of this cutaneous sign of large-vessel vasculitis.

Jul 2009 Giant cell arteritis (GCA) is a systemic vasculitis associated with severe complications such as loss of vision and, rarely, scalp necrosis. We present a patient with GCA who had bilateral scalp necrosis and an erythrocyte sedimentation rate of only ... Read more...

 

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Technical information about 'Giant Cell Arteritis'

Definition: A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)

Descriptor UI: D013700

Alternative terms: Giant Cell Arteritis; Arteritides, Giant Cell; Arteritis, Giant Cell; Giant Cell Arteritides; Horton Giant Cell Arteritis; Arteritis, Giant Cell, Horton's; Giant Cell Arteritis, Horton; Horton's Disease; Hortons Disease; Horton's Giant Cell Arteritis; Horton Disease; Arteritis, Giant Cell, Horton; Cranial Arteritis; Arteritides, Cranial; Arteritis, Cranial; Cranial Arteritides; Temporal Arteritis; Arteritides, Temporal; Temporal Arteritides; Arteritis, Temporal; Aortic Arteritis, Giant Cell; Giant Cell Aortitis; Giant Cell Aortic Arteritis; Giant Cell Aortitis, Horton's; Aortitis, Giant Cell; Aortitides, Giant Cell; Giant Cell Aortitides; Juvenile Temporal Arteritis; Arteritides, Juvenile Temporal; Arteritis, Juvenile Temporal; Juvenile Temporal Arteritides; Temporal Arteritides, Juvenile; Temporal Arteritis, Juvenile;

Related Mesh Headings: Polymyalgia Rheumatica;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.114.875.700; C10.228.140.300.850.500; C14.907.184.438; C14.907.253.946.700; C14.907.940.090.530; C14.907.940.907.700; C17.800.862.252; C20.111.258.962.800;

History Note: 2008 (1963)

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