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Glioma - Diagnosis
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Definition of 'Glioma'

Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

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Saturday, November 21, 2009

Alexander disease: An important mimicker of focal brainstem glioma.

13 Dec 2009 We report the case of a 6-year-old male who was referred to a tertiary oncology center with a focal brainstem lesion which was presumed to be neoplastic. Due to the symmetric nature of the lesion on magnetic resonance imaging, the evaluation was ... Read more...


6-year-old girl with hydrocephalus.

29 Sep 2009 With rare exceptions, pediatric tectal gliomas have been generally reported as low-grade tumors with relatively good prognosis. The patients are usually treated conservatively to manage the signs and symptoms of obstructive hydrocephalus. We report ... Read more...


Robust detection of EGFR copy number changes and EGFR variant III: technical aspects and relevance for glioma diagnostics.

29 Sep 2009 Epidermal growth factor receptor (EGFR) is commonly affected in cancer, generally in the form of an increase in DNA copy number and/or as mutation variants [e.g., EGFR variant III (EGFRvIII), an in-frame deletion of exons 2-7]. While detection of ... Read more...

 

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Technical information about 'Glioma'

Definition: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Descriptor UI: D005910

Alternative terms: Glioma; Gliomas; Glial Cell Tumors; Glial Cell Tumor; Tumor, Glial Cell; Tumors, Glial Cell; Mixed Glioma; Glioma, Mixed; Gliomas, Mixed; Mixed Gliomas; Malignant Glioma; Glioma, Malignant; Gliomas, Malignant; Malignant Gliomas;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secondary; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04.557.465.625.600.380; C04.557.470.670.380; C04.557.580.625.600.380;

Technical Notes: coord IM with precoord CNS/neopl term + site (IM); GLIOMA, SUBEPENDYMAL is available; for sarcomatous GLIOMA use GLIOSARCOMA; for GLIOMA, RETINAL see RETINOBLASTOMA

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