Glucocorticoids
Research News and Information

Thursday, March 18, 2010

Superimposed linear psoriasis: differential therapeutic response of linear and nonlinear lesions.

13 Dec 2009 Linear psoriasis is a very unusual clinical variation of psoriasis. Typical clinical features include early onset of erythematosquamous lesions along Blaschko's lines, ability to elicit psoriatic features, absence of pruritus and positive family ... Read more...

Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response.

29 Nov 2009 BACKGROUND: Glucocorticoids (GCs) play a fundamental role in the treatment of pediatric acute lymphoblastic leukemia (ALL), but therapy with these agents often results in a number of severe side effects. The aim of our study was to evaluate the ... Read more...

Persistent urticaria characterized by recurrent lasting urticarial erythema with histological features of prominent perivascular eosinophilic infiltration.

22 Nov 2009 We report a 29-year-old woman with a 15-year history of recurrent pruritic urticarial erythemas. The individual lesions lasted for > 24 h, and antihistaminic agents were not effective. Histological examination of a skin biopsy revealed interstitial ... Read more...

Latest indexed articles for 'Glucocorticoids'

These are the very latest articles for this heading:

• Superimposed linear psoriasis: differential therapeutic response of linear and nonlinear lesions. 13 Dec 2009
• Response to glucocorticoids and toxicity in childhood acute lymphoblastic leukemia: role of polymorphisms of genes involved in glucocorticoid response. 29 Nov 2009
• Persistent urticaria characterized by recurrent lasting urticarial erythema with histological features of prominent perivascular eosinophilic infiltration. 22 Nov 2009
• Bevacizumab as therapy for radiation necrosis in four children with pontine gliomas. 13 Nov 2009
• The Standard Care vs Corticosteroid for Retinal Vein Occlusion (SCORE) study system for evaluation of optical coherence tomograms: SCORE study report 4. 30 Oct 2009
• An umbrella review: corticosteroid therapy for adults with acute asthma. 30 Oct 2009
• Corticosteroid therapy for severe sepsis and septic shock. 19 Oct 2009
• Corticosteroid therapy for severe sepsis and septic shock. 19 Oct 2009
• [56-year-old patient with leg paresis, pulmonary infiltrates, and eosinophilia--Case 08/2009] 19 Oct 2009
• A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. 18 Oct 2009
• The stressed CNS: when glucocorticoids aggravate inflammation. 13 Oct 2009
• Glucocorticoid use and risk of atrial fibrillation or flutter: a population-based, case-control study. 10 Oct 2009
• Comparison of the spatial distribution of seven types of neuroendocrine neurons in the rat paraventricular nucleus: toward a global 3D model. 8 Oct 2009
• Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development. 7 Oct 2009
• Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. 3 Oct 2009
• The use of intraocular corticosteroids. 29 Sep 2009
• Five-year results of a randomized trial with open-label extension of triamcinolone acetonide for refractory diabetic macular edema. 29 Sep 2009
• The efficacy and duration of intra-articular corticosteroid injection for knee osteoarthritis: a systematic review of level I studies. 29 Sep 2009
• Successful treatment of pemphigus vulgaris with etanercept in four patients. 29 Sep 2009
• Treatment of severe alopecia areata with intralesional steroid injections. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Glucocorticoids'

Definition: A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.

Registry Number: 0

Descriptor UI: D005938

Alternative terms: Glucocorticoids;

Related Mesh Headings: Receptors, Glucocorticoid;

Allowable Qualifiers: blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis;

Tree Number: D06.472.040.543; D27.505.696.399.472.488;

History Note: 67

Technical Notes: GEN: avoid: prefer specifics;