Glucose - Pharmacology
Research News and Information

Sunday, November 22, 2009

Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells.

29 Nov 2009 Bradykinin (BK) is a potent modulator of biological processes in the retina, and retinal pigment epithelial cells (RPE) and the regulation of glutamate are believed to be important in the pathogenesis of diabetic retinopathy. However, the mechanism ... Read more...

Osteoblast differentiation is functionally associated with decreased AMP kinase activity.

29 Nov 2009 Osteoblasts, originating from mesenchymal stem cells, play a pivotal role in bone formation and mineralization. Several transcription factors including runt-related transcription factor 2 (Runx2) have been reported to be essential for osteoblast ... Read more...

AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.

14 Oct 2009 Circadian clocks coordinate behavioral and physiological processes with daily light-dark cycles by driving rhythmic transcription of thousands of genes. Whereas the master clock in the brain is set by light, pacemakers in peripheral organs, such as ... Read more...

Latest indexed articles for 'Glucose - Pharmacology'

These are the very latest articles for this heading:

• Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells. 29 Nov 2009
• Osteoblast differentiation is functionally associated with decreased AMP kinase activity. 29 Nov 2009
• AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. 14 Oct 2009
• Effect of pyruvate, lactate and insulin on ATP supply and demand in unpaced perfused rat heart. 10 Oct 2009
• Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions. 29 Sep 2009
• Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid. 28 Sep 2009
• Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels. 28 Sep 2009
• High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells. 12 Sep 2009
• A novel decoy that interrupts G93A-superoxide dismutase gain of interaction with malate dehydrogenase improves survival in an amyotrophic lateral sclerosis cell model. 8 Sep 2009
• Fentanyl inhibits glucose-stimulated insulin release from beta-cells in rat pancreatic islets. 5 Sep 2009
• Impact of the transfer of sFlt-1 gene fragments on the ERK1/2 pathway of VEGF in vitro. 30 Aug 2009
• Role of IL-1beta on the glutamine synthetase in retinal Müller cells under high glucose conditions. 30 Aug 2009
• [Metabolism characteristics of Chelativorans oligotrophicus by two-phase growth on the mixture of EDTA and glucose] 30 Aug 2009
• Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism. 30 Aug 2009
• Optimization of coprogen production in Neurospora crassa. 30 Aug 2009
• High extracellular glucose inhibits exocytosis through disruption of syntaxin 1A-containing lipid rafts. 26 Aug 2009
• Epinephrine-induced hyperpolarization of pancreatic islet cells is sensitive to PI3K-PDK1 signaling. 25 Aug 2009
• Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle. 24 Aug 2009
• Glucose enhances collectrin protein expression in insulin-producing MIN6 beta cells. 24 Aug 2009
• Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM). 2 Aug 2009

See a longer list of these articles.

Technical information about 'Glucose'

Definition: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

Chemical name: D-Glucose

Registry Number: 50-99-7

Descriptor UI: D005947

Alternative terms: Glucose; Dextrose; D-Glucose; D Glucose; Glucose, (L)-Isomer; L-Glucose; L Glucose; Glucose, (beta-D)-Isomer; Glucose, (DL)-Isomer; Glucose Monohydrate; Monohydrate, Glucose; Glucose, (alpha-D)-Isomer;

Related Mesh Headings: Blood Glucose; Glycosuria; Hyperglycemia; Hypoglycemia;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; chemistry; contraindications; agonists;

Pharmacological Action: Sweetening Agents;

Tree Number: D09.546.359.448;

Online Note: use GLUCOSE to search GLUCOSE INJECTION 1966

History Note: /metabolism was GLUCOSE METABOLISM 1965; GLUCOSE INJECTION was heading 1963-66

Technical Notes: /blood = BLOOD GLUCOSE but consider also HYPERGLYCEMIA & HYPOGLYCEMIA; /defic: consider also HYPOGLYCEMIA