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Glucosyltransferases - Metabolism
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Definition of 'Glucosyltransferases'

Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.

Common names: Glucosyltransferases

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Sunday, November 22, 2009

Ceramide metabolism determines glioma cell resistance to chemotherapy.

29 Nov 2009 Tumor cell resistance to chemotherapy constitutes a major problem in the treatment of malignant tumors. We here investigated the role of ceramide metabolism for the resistance of glioma cells to treatment with the chemotherapeutic drug, gemcitabine. ... Read more...


A novel glucosyltransferase involved in O-antigen modification of Shigella flexneri serotype 1c.

26 Aug 2009 The O antigen of serotype 1c differs from the unmodified O antigen of serotype Y by the addition of a disaccharide (two glucosyl groups) to the tetrasaccharide repeating unit. It was shown here that addition of the first glucosyl group is mediated ... Read more...


Reduction of lysyl hydroxylase 3 causes deleterious changes in the deposition and organization of extracellular matrix.

18 Aug 2009 Lysyl hydroxylase 3 (LH3) is a multifunctional enzyme possessing lysyl hydroxylase, collagen galactosyltransferase, and glucosyltransferase (GGT) activities. We report here an important role for LH3 in the organization of the extracellular matrix ... Read more...

 

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Technical information about 'Glucosyltransferases'

Definition: Enzymes that catalyze the transfer of glucose from a nucleoside diphosphate glucose to an acceptor molecule which is frequently another carbohydrate. EC 2.4.1.-.

Registry Number: EC 2.4.1.-

Descriptor UI: D005964

Alternative terms: Glucosyltransferases;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.913.400.450.460;

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