Glutathione - Metabolism
Research News and Information

Monday, November 23, 2009

Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells.

13 Nov 2009 PURPOSE: Free radicals are believed to play an active role in the bystander response. This study investigated their origin as well as their temporal and spatial impacts in the bystander effect. METHODS AND MATERIALS: We employed a precise ... Read more...

Safener responsiveness and multiple herbicide resistance in the weed black-grass (Alopecurus myosuroides).

29 Sep 2009 Safeners enhance the selectivity of graminicidal herbicides such as fenoxaprop ethyl in cereals, by increasing their rates of detoxification in the crop. While studying the selectivity of fenoxaprop ethyl in wheat, we determined that the safeners ... Read more...

Genotoxic and oxidative stress-inducing effects of deltamethrin in the erythrocytes of a freshwater biomarker fish species, Channa punctata Bloch.

29 Sep 2009 Deltamethrin, an alpha-cyano class of pyrethroid insecticide is used in insect pest control and antimalaria programs in several countries including India. Although various toxic manifestations of deltamethrin are reported in mammals, its ... Read more...

Latest indexed articles for 'Glutathione - Metabolism'

These are the very latest articles for this heading:

• Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells. 13 Nov 2009
• Safener responsiveness and multiple herbicide resistance in the weed black-grass (Alopecurus myosuroides). 29 Sep 2009
• Genotoxic and oxidative stress-inducing effects of deltamethrin in the erythrocytes of a freshwater biomarker fish species, Channa punctata Bloch. 29 Sep 2009
• Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid. 28 Sep 2009
• Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass. 16 Sep 2009
• Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. 14 Sep 2009
• Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells. 9 Sep 2009
• 12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress. 6 Sep 2009
• Altered pH homeostasis modulates the glutathione peroxidase mimics and other antioxidant properties of diphenyl diselenide. 4 Sep 2009
• Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism. 2 Sep 2009
• Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cells. 30 Aug 2009
• Glutathione and amino acid concentrations in human liver during short warm ischaemia and reperfusion: a pilot study. 30 Aug 2009
• Effect of acute and chronic administration of progesterone, estrogen, FSH and LH on oxidant and antioxidant parameters in rat gastric tissue. 30 Aug 2009
• Differential response of antioxidative defense system of Anabaena doliolum under arsenite and arsenate stress. 30 Aug 2009
• Characterization of tanshinones with quinone reductase induction activity from Radix Salvia miltiorrhiza by liquid chromatography/tandem mass spectrometry. 30 Aug 2009
• Simultaneous analysis of (13)C-glutathione as its dimeric form GSSG and its precursor [1-(13)C]glycine using liquid chromatography/isotope ratio mass spectrometry. 30 Aug 2009
• Biochemical, behavioural and quantitative alterations in cerebellum of Swiss albino mice following irradiation and its modulation by Grewia asiatica. 30 Aug 2009
• Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants. 30 Aug 2009
• Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead. 27 Aug 2009
• Physiological levels of glutathione enhance Zn(II) binding by a Cys4 zinc finger. 26 Aug 2009

See a longer list of these articles.

Technical information about 'Glutathione'

Definition: A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

Chemical name: Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-

Registry Number: 70-18-8

Descriptor UI: D005978

Alternative terms: Glutathione; gamma-L-Glutamyl-L-Cysteinylglycine; gamma L Glutamyl L Cysteinylglycine; gamma-L-Glu-L-Cys-Gly; gamma L Glu L Cys Gly; Reduced Glutathione; Glutathione, Reduced;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.456.448;