Glutathione
Research News and Information

Saturday, November 21, 2009

Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling.

29 Nov 2009 The role of OxLDL in the generation and progression of atherosclerosis is well admitted. In addition, it is well known that atherosclerosis is often accompanied by perturbations in bone remodeling, resulting in osteoporosis. In the current studies, ... Read more...

Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells.

13 Nov 2009 PURPOSE: Free radicals are believed to play an active role in the bystander response. This study investigated their origin as well as their temporal and spatial impacts in the bystander effect. METHODS AND MATERIALS: We employed a precise ... Read more...

Comparison of preservation solutions in an experimental model of organ cooling in kidney transplantation.

29 Sep 2009 BACKGROUND: Viscous preservation solutions such as University of Wisconsin solution (UW) may be less effective at rapid removal of blood from an organ so that cooling takes longer. This study assessed the temperature changes of kidneys flushed with ... Read more...

Latest indexed articles for 'Glutathione'

These are the very latest articles for this heading:

• Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. 29 Nov 2009
• Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells. 13 Nov 2009
• Comparison of preservation solutions in an experimental model of organ cooling in kidney transplantation. 29 Sep 2009
• Detection of aminothiols through surface-assisted laser desorption/ionization mass spectrometry using mixed gold nanoparticles. 29 Sep 2009
• Safener responsiveness and multiple herbicide resistance in the weed black-grass (Alopecurus myosuroides). 29 Sep 2009
• Genotoxic and oxidative stress-inducing effects of deltamethrin in the erythrocytes of a freshwater biomarker fish species, Channa punctata Bloch. 29 Sep 2009
• Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid. 28 Sep 2009
• Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass. 16 Sep 2009
• Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. 14 Sep 2009
• Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells. 9 Sep 2009
• 12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress. 6 Sep 2009
• Altered pH homeostasis modulates the glutathione peroxidase mimics and other antioxidant properties of diphenyl diselenide. 4 Sep 2009
• Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism. 2 Sep 2009
• Blood glutathione and subclinical atherosclerosis in African men: the SABPA Study. Sep 2009
• Increased oxidative stress in the airway and development of allergic inflammation in a mouse model of asthma. 30 Aug 2009
• alpha-Luminol prevents decreases in glutamate, glutathione, and glutamine synthetase in the retinas of glaucomatous DBA/2J mice. 30 Aug 2009
• Hepatoprotection of chlorella against carbon tetrachloride-induced oxidative damage in rats. 30 Aug 2009
• Endothelial nitric oxide synthase is up-regulated in the umbilical cord in pregnancies complicated with intrauterine growth retardation. 30 Aug 2009
• Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cells. 30 Aug 2009
• Glutathione and amino acid concentrations in human liver during short warm ischaemia and reperfusion: a pilot study. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Glutathione'

Definition: A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

Chemical name: Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-

Registry Number: 70-18-8

Descriptor UI: D005978

Alternative terms: Glutathione; gamma-L-Glutamyl-L-Cysteinylglycine; gamma L Glutamyl L Cysteinylglycine; gamma-L-Glu-L-Cys-Gly; gamma L Glu L Cys Gly; Reduced Glutathione; Glutathione, Reduced;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.456.448;