Glycine - Pharmacology
Research News and Information

Monday, March 22, 2010

T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids.

19 Oct 2009 Lipoamino acids are anandamide-related endogenous molecules that induce analgesia via unresolved mechanisms. Here, we provide evidence that the T-type/Cav3 calcium channels are important pharmacological targets underlying their physiological ... Read more...

Weed control in glyphosate-tolerant maize in Europe.

29 Sep 2009 Maize growing in the EU27 increased to over 13 million ha in 2007, most of which (>80%) was grown in just eight countries (France, Romania, Germany, Hungary, Italy, Poland, Spain and Bulgaria). The number of herbicides used to control the wide ... Read more...

Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells.

21 Sep 2009 In the main olfactory bulb, activation of group I metabotropic glutamate receptors (mGluRs) by olfactory nerve stimulation generates slow (2 Hz) oscillations near the basal respiratory frequency. These oscillations arise in the glomerular layer and ... Read more...

Latest indexed articles for 'Glycine - Pharmacology'

These are the very latest articles for this heading:

• T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids. 19 Oct 2009
• Weed control in glyphosate-tolerant maize in Europe. 29 Sep 2009
• Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells. 21 Sep 2009
• Differences in the activation of inhibitory motoneuron receptors in the frog Rana ridibunda by GABA and glycine and their interaction. 21 Sep 2009
• Negative shift in the glycine reversal potential mediated by a Ca2+- and pH-dependent mechanism in interneurons. 14 Sep 2009
• Isocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa. 19 Aug 2009
• Horseweed with reduced susceptibility to glyphosate found in the czech republic. 10 Aug 2009
• Behavioural profile of selective ligands for mGlu7 and mGlu8 glutamate receptors in agonistic encounters between mice. 30 Jul 2009
• Surfactant-induced deposit structures in relation to the biological efficacy of glyphosate on easy- and difficult-to-wet weed species. 30 Jul 2009
• Fragile X mental retardation protein is required for chemically-induced long-term potentiation of the hippocampus in adult mice. 28 Jul 2009
• Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy. 28 Jul 2009
• Activation of metabotropic glutamate receptor type 2/3 supports the involvement of the hippocampal mossy fiber pathway on contextual fear memory consolidation. 26 Jul 2009
• Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide. 21 Jul 2009
• Calcium leads to further increase in glycine-enhanced extracellular secretion of recombinant alpha-cyclodextrin glycosyltransferase in Escherichia coli. 20 Jul 2009
• Glycine inhibits the LPS-induced increase in cytosolic Ca2+ concentration and TNFalpha production in cardiomyocytes by activating a glycine receptor. 18 Jul 2009
• Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum. 15 Jul 2009
• Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiation. 14 Jul 2009
• Novel mGluR- and CB1R-independent suppression of GABA release caused by a contaminant of the group I metabotropic glutamate receptor agonist, DHPG. 29 Jun 2009
• Ethylene evolution changes in tilted Fraxinus mandshurica Rupr. var. japonica maxim. seedlings in relation to tension wood formation. 29 Jun 2009
• The interactive effects of glycine, total sulfur amino acids, and lysine supplementation to corn-soybean meal diets on growth performance and serum uric acid and urea concentrations in broilers. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Glycine'

Definition: A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

Chemical name: 2-aminoacetic acid

Registry Number: 56-40-6

Descriptor UI: D005998

Alternative terms: Glycine; Aminoacetic Acid; Acid, Aminoacetic; Glycine Carbonate (1:1), Monosodium Salt; Glycine Carbonate (2:1), Monolithium Salt; Glycine Carbonate (2:1), Monopotassium Salt; Glycine Carbonate (2:1), Monosodium Salt; Glycine Hydrochloride; Hydrochloride, Glycine; Glycine Hydrochloride (2:1); Glycine, Monosodium Salt; Monosodium Salt Glycine; Salt Glycine, Monosodium; Glycine Phosphate (1:1); Glycine Sulfate (3:1); Glycine, Calcium Salt; Calcium Salt Glycine; Glycine, Calcium Salt (2:1); Glycine, Cobalt Salt; Cobalt Salt Glycine; Glycine, Copper Salt; Copper Salt Glycine; Glycine, Monoammonium Salt; Monoammonium Salt Glycine; Salt Glycine, Monoammonium; Glycine, Monopotasssium Salt; Monopotasssium Salt Glycine; Glycine, Sodium Hydrogen Carbonate; Glycine Phosphate; Phosphate, Glycine;

Related Mesh Headings: Receptors, Glycine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Glycine Agents;

Tree Number: D12.125.481;