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Glycosylation
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Definition of 'Glycosylation'

The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.

Common names: Glycosylation; Glycosylations; Protein Glycosylation; Glycosylation, Protein; Glycosylations, Protein; Protein Glycosylations

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Saturday, November 21, 2009

Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.

30 Oct 2009 HIV-1 Nef accelerates the progression to AIDS by binding with and activating a Src kinase Hck, but underlying molecular basis is not understood. We revealed that Nef disturbed N-glycosylation/trafficking of a cytokine receptor Fms in an ... Read more...


Correctors enhance maturation of DeltaF508 CFTR by promoting interactions between the two halves of the molecule.

18 Oct 2009 Deletion of Phe508 in cystic fibrosis transmembrane conductance regulator (DeltaF508 CFTR) causes cystic fibrosis. CFTR consists of two homologous halves with each containing a nucleotide-binding domain (NBD) and a transmembrane domain (TMD). ... Read more...


Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the alpha7 acetylcholine receptor through a cytoplasmic coiled-coil domain.

5 Oct 2009 RIC-3 (resistant to inhibitor of cholinesterase) is a transmembrane protein, found in invertebrates and vertebrates, that modulates the surface expression of a variety of nicotinic acetylcholine receptors (nAChRs) in neurons and other cells. To ... Read more...

 

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Technical information about 'Glycosylation'

Definition: The chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, especially peptides or proteins. Glycosyl transferases are used in this biochemical reaction.

Descriptor UI: D006031

Alternative terms: Glycosylation; Glycosylations; Protein Glycosylation; Glycosylation, Protein; Glycosylations, Protein; Protein Glycosylations;

Related Mesh Headings: Protein Processing, Post-Translational; Glycosylation End Products, Advanced;

Allowable Qualifiers: drug effects; radiation effects;

Tree Number: G02.111.087.160.812; G02.149.115.160.812; G02.149.465.350; G02.607.750.350; G03.495.256.812;

History Note: 87

Technical Notes: almost never IM

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