Growth Disorders
Research News and Information

Sunday, November 22, 2009

aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues.

22 Sep 2009 Adipose tissue is one of the major sites for fatty acid synthesis and lipid storage. We generated adipose (fat)-specific ACC1 knockout (FACC1KO) mice using the aP2-Cre/loxP system. FACC1KO mice showed prenatal growth retardation; after weaning, ... Read more...

Mechanisms of growth impairment in pediatric Crohn's disease.

30 Aug 2009 Crohn's disease manifests during childhood or adolescence in up to 25% of patients. The potential for linear growth impairment as a complication of chronic intestinal inflammation is unique to pediatric patient populations. Insulin-like growth ... Read more...

Recombinant human insulin-like growth factor-1 treatment: ready for primetime.

30 Aug 2009 The combination of targeted gene knockout studies in animals and human mutational analysis has demonstrated the key role of the IGF system in mammalian growth, both in utero and postnatally. The concept of IGF deficiency as a diagnostic category for ... Read more...

Latest indexed articles for 'Growth Disorders'

These are the very latest articles for this heading:

• Treatment with GH in adults with GH deficiency. Foreword. 4 Oct 2009
• aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues. 22 Sep 2009
• Mechanisms of growth impairment in pediatric Crohn's disease. 30 Aug 2009
• Recombinant human insulin-like growth factor-1 treatment: ready for primetime. 30 Aug 2009
• Strategies for maximizing growth in puberty in children with short stature. 30 Aug 2009
• Growth hormone: the expansion of available products and indications. 30 Aug 2009
• Growth assessment of paediatric patients with CF comparing different auxologic indicators: A multicentre Italian study. 30 Aug 2009
• The recognition and treatment of growth disorders - a 50-year retrospective. 30 Aug 2009
• Growth and chronic disease: findings in the Helsinki Birth Cohort. 30 Aug 2009
• Target height estimation in children with idiopathic short stature who are referred to the growth clinic. 30 Aug 2009
• Abnormal responses to TRH in children born small for gestational age that failed to catch up. 30 Aug 2009
• Stimulant medication use and response to growth hormone therapy: an NCGS database analysis. 30 Aug 2009
• Diagnosis of growth hormone deficiency by using the arginine provocative test: is it possible to shorten testing time without altering validity? 30 Aug 2009
• [Growth: what is normal?] 24 Aug 2009
• Stability, adaptation and growth following distraction osteogenesis in the craniofacial region. 30 Jul 2009
• Gastrostomy placement improves height and weight gain in girls with Rett syndrome. 30 Jul 2009
• Patient, physician, and consumer drivers: referrals for short stature and access to specialty drugs. 30 Jul 2009
• Some indicators of nutritional status are associated with activity and exploration in infants at risk for vitamin and mineral deficiencies. 27 Jul 2009
• SCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice. 25 Jul 2009
• Cartilage oligomeric matrix protein in patients with juvenile idiopathic arthritis: relation to growth and disease activity. 13 Jul 2009

See a longer list of these articles.

Technical information about 'Growth Disorders'

Definition: Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.

Descriptor UI: D006130

Alternative terms: Growth Disorders; Disorder, Growth; Growth Disorder;

Related Mesh Headings: Bone Diseases, Developmental; Dwarfism; Gigantism;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C23.550.393;

History Note: 72(69)

Technical Notes: do not confuse with NUTRITION DISORDERS (disord of assimilating & utilizing nutrients)