Guanylate Kinase
Research News and Information

Sunday, November 22, 2009

Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase.

21 Jul 2009 Vaccinia virus thymidylate kinase, although similar in sequence to human TMP kinase, has broader substrate specificity and phosphorylates (E)-5-(2-bromovinyl)-dUMP and dGMP. Modified guanines such as glyoxal-dG, 8-oxo-dG, O(6)-methyl-dG, ... Read more...

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway.

18 Jul 2009 Synaptic plasticity is dependent on the differential sorting, delivery and retention of neurotransmitter receptors, but the mechanisms underlying these processes are poorly understood. We found that differential sorting of glutamate receptor ... Read more...

Crumbs stabilises epithelial polarity during tissue remodelling.

28 Jun 2009 The apicobasal polarity of epithelia depends on the integrated activity of apical and basolateral proteins, and is essential for tissue integrity and body homeostasis. Yet these tissues are frequently on the move as they are sculpted by active ... Read more...

Latest indexed articles for 'Guanylate Kinase'

These are the very latest articles for this heading:

• Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase. 21 Jul 2009
• SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway. 18 Jul 2009
• Crumbs stabilises epithelial polarity during tissue remodelling. 28 Jun 2009
• Neuron-specific regulation of associative learning and memory by MAGI-1 in C. elegans. 22 Jun 2009
• Productive versus unproductive nucleotide binding in yeast guanylate kinase mutants: comparison of R41M with K14M by proton two dimensional transferred NOESY. 21 Jun 2009
• Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex. 15 Jun 2009
• How to build a tight but permeable glomerular junction. 9 Jun 2009
• Slit diaphragms contain tight junction proteins. 26 May 2009
• Functional dissection of the intramolecular Src homology 3-guanylate kinase domain coupling in voltage-gated Ca2+ channel beta-subunits. 6 May 2009
• MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface. 27 Apr 2009
• Human calcium/calmodulin-dependent serine protein kinase regulates the expression of p21 via the E2A transcription factor. 13 Apr 2009
• Elastic energy driven polymerization. 16 Mar 2009
• CASK point mutation regulates protein-protein interactions and NR2b promoter activity. 7 Mar 2009
• Intramolecular interactions between the SRC homology 3 guanylate kinase domains of discs large regulate its function in asymmetric cell division. 2 Mar 2009
• MAGI-1 modulates AMPA receptor synaptic localization and behavioral plasticity in response to prior experience. 24 Feb 2009
• Mutations at serine 37 in mouse guanylate kinase confer resistance to 6-thioguanine. 8 Jan 2009
• Origin of the voltage dependence of G-protein regulation of P/Q-type Ca2+ channels. 22 Dec 2008
• Acheron, an novel LA antigen family member, binds to CASK and forms a complex with Id transcription factors. 16 Dec 2008
• Increased IP3/Ca2+ signaling compensates depletion of LET-413/DLG-1 in C. elegans epithelial junction assembly. 5 Dec 2008
• Polarized targeting of neurexins to synapses is regulated by their C-terminal sequences. 24 Nov 2008

See a longer list of these articles.

Technical information about 'Guanylate Kinase'

Definition: Catalyzes the ATP-dependent PHOSPHORYLATION of GMP to generate GDP and ADP.

Registry Number: EC 2.7.4.8

Descriptor UI: D051528

Alternative terms: Guanylate Kinase; Kinase, Guanylate; GMP Kinase; Kinase, GMP; Guanosine Monophosphate Kinase; Kinase, Guanosine Monophosphate; Monophosphate Kinase, Guanosine; ATP-(d)GMP Phosphotransferase; Guanylate Kinase 1; Kinase 1, Guanylate; Membrane-Associated Guanylate Kinase; Guanylate Kinase, Membrane-Associated; Kinase, Membrane-Associated Guanylate; Membrane Associated Guanylate Kinase; Erythrocyte protein p55; p55, Erythrocyte protein; protein p55, Erythrocyte;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.913.696.650.450;

History Note: 2006(1980); use NUCLEOSIDE-PHOSPHATE KINASE 1979, & NUCLEOTIDES & PHOSPHOTRANSFERASES, ATP 1974-1978