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Hair Cells, Auditory
Research News and Information
Definition of 'Hair Cells, Auditory'Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the cochlea. Towards the cochlear apex, the length of hair cell bodies and their apical stereocilia increase, allowing differential responses to various frequencies of sound. |
Sunday, November 22, 2009
Mechanotransduction by hair cells: models, molecules, and mechanisms.
30 Sep 2009
Mechanotransduction, the transformation of mechanical force into an electrical signal, allows living organisms to hear, register movement and gravity, detect touch, and sense changes in cell volume and shape. Hair cells in the inner ear are ... Read more...
Hepatocyte growth factor protects auditory hair cells from aminoglycosides.
29 Sep 2009
OBJECTIVES/HYPOTHESIS: To examine the effect of hepatocyte growth factor (HGF) for protection of auditory hair cells against aminoglycosides and its molecular mechanisms. STUDY DESIGN: Experimental study. METHODS: We quantitatively assessed ... Read more...
Transplantation of mouse induced pluripotent stem cells into the cochlea.
21 Sep 2009
This study examined the potential of induced pluripotent stem (iPS) cells for use as a source of transplants for the restoration of auditory spiral ganglion neurons. We monitored neurite outgrowth from iPS cell-derived neural progenitors toward ... Read more...
Latest indexed articles for 'Hair Cells, Auditory'
These are the very latest articles for this heading:
- Mechanotransduction by hair cells: models, molecules, and mechanisms.
30 Sep 2009 - Hepatocyte growth factor protects auditory hair cells from aminoglycosides.
29 Sep 2009 - Transplantation of mouse induced pluripotent stem cells into the cochlea.
21 Sep 2009 - Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D.
10 Sep 2009 - Zebrafish ale oko, an essential determinant of sensory neuron survival and the polarity of retinal radial glia, encodes the p50 subunit of dynactin.
30 Aug 2009 - The mechanotransduction machinery of hair cells.
23 Aug 2009 - CLRN1 is nonessential in the mouse retina but is required for cochlear hair cell development.
12 Aug 2009 - Chondrocyte-specific Smad4 gene conditional knockout results in hearing loss and inner ear malformation in mice.
30 Jul 2009 - Potential novel drug carriers for inner ear treatment: hyperbranched polylysine and lipid nanocapsules.
30 Jul 2009 - Mitochondria modulate the spatio-temporal properties of intra- and intercellular Ca2+ signals in cochlear supporting cells.
21 Jul 2009 - The large-conductance Ca(2+)-activated K(+) channel interacts with the apolipoprotein ApoA1.
16 Jul 2009 - Building the world's best hearing aid; regulation of cell fate in the cochlea.
11 Jul 2009 - Efferent control of hair cell and afferent responses in the semicircular canals.
29 Jun 2009 - Amplifying effect of a release mechanism for fast adaptation in the hair bundle.
29 Jun 2009 - Ameliorative effects of an augmented acoustic environment on age-related hearing loss in middle-aged Fischer 344/NHsd rats.
29 Jun 2009 - Seasonal plasticity of auditory saccular sensitivity in the vocal plainfin midshipman fish, Porichthys notatus.
22 Jun 2009 - Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors.
14 Jun 2009 - Spontaneous otoacoustic emissions in lizards: a comparison of the skink-like lizard families Cordylidae and Gerrhosauridae.
14 Jun 2009 - The unitary event underlying multiquantal EPSCs at a hair cell's ribbon synapse.
8 Jun 2009 - DNA sequence analysis of SLC26A5, encoding prestin, in a patient-control cohort: identification of fourteen novel DNA sequence variations.
31 May 2009
See a longer list of these articles.
Technical information about 'Hair Cells, Auditory'
Definition: Sensory cells in the organ of Corti, characterized by their apical stereocilia (hair-like projections). The inner and outer hair cells, as defined by their proximity to the core of spongy bone (the modiolus), change morphologically along the cochlea. Towards the cochlear apex, the length of hair cell bodies and their apical stereocilia increase, allowing differential responses to various frequencies of sound.
Descriptor UI: D006198
Alternative terms: Hair Cells, Auditory; Auditory Hair Cell; Hair Cell, Auditory; Auditory Hair Cells;
Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;
Tree Number: A08.663.650.250; A08.663.650.915.750.600.350; A08.800.950.750.600.350; A09.246.631.246.577.325; A11.671.650.250; A11.671.650.915.750.600.350;
History Note: 2008 (1977)