Heart - Drug effects
Research News and Information

Monday, November 23, 2009

Development and evaluation of a novel solution, Somah, for the procurement and preservation of beating and nonbeating donor hearts for transplantation.

10 Oct 2009 BACKGROUND: Injury to myocytes, endocardium, and the coronary endothelium during harvesting and storage can compromise outcomes after heart transplantation. Safeguarding of structure and function of cardiomyocytes and endothelium in donor hearts may ... Read more...

IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction.

23 Sep 2009 IL-18 is a proinflammatory cytokine known to cause tissue injury by inducing inflammation and cell death. Increased levels of IL-18 are associated with myocardial injury after ischemia or infarction. IL-18-binding protein (IL-18BP), the naturally ... Read more...

Qiliqiangxin regulates the balance between tumor necrosis factor-alpha and interleukin-10 and improves cardiac function in rats with myocardial infarction.

9 Sep 2009 The study investigated the effects of traditional Chinese drug Qiliqiangxin on cardiac function and the expression of pro/anti-inflammatory cytokines TNF-alpha/IL-10 in rats with myocardial infarction (MI). Rats with MI were randomly divided into ... Read more...

Latest indexed articles for 'Heart - Drug effects'

These are the very latest articles for this heading:

• Development and evaluation of a novel solution, Somah, for the procurement and preservation of beating and nonbeating donor hearts for transplantation. 10 Oct 2009
• IL-18 binding protein-expressing mesenchymal stem cells improve myocardial protection after ischemia or infarction. 23 Sep 2009
• Qiliqiangxin regulates the balance between tumor necrosis factor-alpha and interleukin-10 and improves cardiac function in rats with myocardial infarction. 9 Sep 2009
• Effects of diabetes mellitus, pressure-overload and their association on myocardial structure and function. 8 Sep 2009
• Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker. 6 Sep 2009
• Chronic effects of dietary carbohydrate variation on [18F]-2-fluoro-2-deoxyglucose uptake in rodent heart. 30 Aug 2009
• Neutral endopeptidase inhibition enhances substance P mediated inflammation due to hypomagnesemia. 30 Aug 2009
• Deferasirox removes cardiac iron and attenuates oxidative stress in the iron-overloaded gerbil. 30 Aug 2009
• Long-term therapy with deflazacort decreases myocardial fibrosis in mdx mice. 30 Aug 2009
• Trastuzumab (Herceptin)-associated cardiomyopathy presented as new onset of complete left bundle-branch block mimicking acute coronary syndrome: a case report and literature review. 30 Aug 2009
• Fishing in the (deoxyribonucleotide) pool. 25 Aug 2009
• Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity. 25 Aug 2009
• Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus. 24 Aug 2009
• Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. 22 Aug 2009
• Nitrite therapy after cardiac arrest reduces reactive oxygen species generation, improves cardiac and neurological function, and enhances survival via reversible inhibition of mitochondrial complex I. 22 Aug 2009
• Effects of monovalent cations on Ca2+ uptake by skeletal and cardiac muscle sarcoplasmic reticulum. 21 Aug 2009
• Freshly crushed garlic is a superior cardioprotective agent than processed garlic. 10 Aug 2009
• Differential pulmonary and cardiac effects of pulmonary exposure to a panel of particulate matter-associated metals. 9 Aug 2009
• Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. 4 Aug 2009
• Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats. 3 Aug 2009

See a longer list of these articles.

Technical information about 'Heart'

Definition: The hollow, muscular organ that maintains the circulation of the blood.

Descriptor UI: D006321

Alternative terms: Heart; Hearts;

Related Mesh Headings: Angiocardiography; Anti-Arrhythmia Agents; Ballistocardiography; Cardiotonic Agents; Electrocardiography; Myocardium;

Allowable Qualifiers: anatomy & histology; drug effects; embryology; growth & development; innervation; microbiology; parasitology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; virology;

Tree Number: A07.541;

Technical Notes: heart as pump, not tissue (MYOCARDIUM); qualif permitted: /anat /drug eff /embryol (FETAL HEART also exists) /growth /innerv (HEART CONDUCTION SYSTEM also exists) /microbiol /parasitol /physiol (see also ATRIAL FUNCTION & VENTRICULAR FUNCTION & their specifics; see also MYOCARDIAL CONTRACTION & its specifics) /physiopathol /rad eff /radiogr (do not confuse with ANGIOCARDIOGRAPHY) /radionuclide /virol; /blood supply = CORONARY VESSELS but consider also CORONARY CIRCULATION; /drug eff: consider also MYOCARDIAL DEPRESSANTS see ANTI-ARRHYTHMIA AGENTS & CARDIOTONIC AGENTS; /transpl = HEART TRANSPLANTATION: do not coord with TRANSPLANTATION, HOMOLOGOUS unless particularly discussed; /ultrasonogr = ECHOCARDIOGRAPHY or ECHOCARDIOGRAPHY, DOPPLER; inotropism: INOTROPISM, CARDIAC see MYOCARDIAL CONTRACTION & INOTROPIC AGENTS, POSITIVE CARDIAC are available but see MYOCARDIAL CONTRACTION note; chronotropism: see HEART RATE note; DIASTOLE & SYSTOLE are also available; heart-lung prep: index HEART /physiol (probably NIM); Manual 21.48+; carditis = MYOCARDITIS; mural thrombosis: index HEART DIS (IM) + THROMBOSIS (IM)