Heart Defects, Congenital - Chemically induced
Research News and Information

Friday, March 19, 2010

Angioarchitecture of the venous and capillary system in heart defects induced by retinoic acid in mice.

29 Jun 2009 BACKGROUND: Corrosion casting and immunohistochemical staining with anti-alpha smooth muscle actin and anti-CD34 was utilized to demonstrate the capillary plexus and venous system in control and malformed mouse hearts. METHODS: Outflow tract ... Read more...

Developmental toxicity of ethanol in chick heart in ovo and in micromass culture can be prevented by addition of vitamin C and folic acid.

8 Apr 2009 The teratogenic effects of ethanol include malformations of the cardiovascular system, which may be abrogated by multivitamin therapy. Chick cardiomyocytes in micromass culture were treated with ethanol alone or with supplementation with folate or ... Read more...

Maternal use of antihypertensive drugs in early pregnancy and delivery outcome, notably the presence of congenital heart defects in the infants.

5 Feb 2009 PURPOSE: To investigate the association between maternal use of antihypertensives in early pregnancy and delivery outcome, notably infant congenital malformations. METHODS: A cohort study of 1,418 women who had used antihypertensive drugs in early ... Read more...

Latest indexed articles for 'Heart Defects, Congenital - Chemically induced'

These are the very latest articles for this heading:

• SSRIs and heart defects in neonates. 19 Oct 2009
• GlaxoSmithKline told to pay family $2.5m after jury finds paroxetine caused son's heart defects. 13 Oct 2009
• GSK is sued in US over alleged link of paroxetine to birth defects. 10 Oct 2009
• Cardiovascular effects of noncardiovascular drugs. 20 Sep 2009
• Angioarchitecture of the venous and capillary system in heart defects induced by retinoic acid in mice. 29 Jun 2009
• Developmental toxicity of ethanol in chick heart in ovo and in micromass culture can be prevented by addition of vitamin C and folic acid. 8 Apr 2009
• Maternal use of antihypertensive drugs in early pregnancy and delivery outcome, notably the presence of congenital heart defects in the infants. 5 Feb 2009
• Depression in pregnant adolescents: considerations for treatment. 30 Jan 2009
• High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. 30 Jan 2009
• Maternal asthma, asthma medication use, and the risk of congenital heart defects. 30 Jan 2009
• Should paroxetine be used to treat depression during pregnancy? 30 Oct 2008
• Does paroxetine cause cardiac malformations? 30 Jul 2008
• PCB126 exposure disrupts zebrafish ventricular and branchial but not early neural crest development. 24 Jul 2008
• Maternal use of antipsychotics in early pregnancy and delivery outcome. 30 May 2008
• Folic acid and methionine in the prevention of teratogen-induced congenital defects in mice. 13 Apr 2008
• Monozygotic twins discordant for VACTERL association. 30 Mar 2008
• Evaluation of the risk of congenital cardiovascular defects associated with use of paroxetine during pregnancy. 30 Mar 2008
• Development of the morpholino gene knockdown technique in Fundulus heteroclitus: a tool for studying molecular mechanisms in an established environmental model. 21 Feb 2008
• Cardiac malformations are increased in infants of mothers with epilepsy. 6 Jan 2008
• The developing embryonic cardiac outflow tract is highly sensitive to oxidant stress. 29 Nov 2007

See a longer list of these articles.

Technical information about 'Heart Defects, Congenital'

Definition: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Descriptor UI: D006330

Alternative terms: Heart Defects, Congenital; Congenital Heart Defect; Defect, Congenital Heart; Heart Defect, Congenital; Defects, Congenital Heart; Heart Abnormalities; Abnormality, Heart; Abnormalities, Heart; Heart Abnormality; Congenital Heart Defects;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; virology;

Tree Number: C14.240.400; C14.280.400; C16.131.240.400;

Technical Notes: general only; do not use as coordinate for specific term /abnorm; cyanotic defects probably go here but do not also index under CYANOSIS unless especially discussed