Heat-Shock Proteins - Genetics
Research News and Information

Monday, November 23, 2009

The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I.

29 Sep 2009 Tapasin (Tpn) is an ER chaperone that is uniquely dedicated to MHC-I biosynthesis. It binds MHC-I molecules, integrates them into peptide-loading complexes, and exerts quality control of the bound peptides; only when an "optimal peptide" is bound ... Read more...

The determinant of potyvirus ability to overcome the RTM resistance of Arabidopsis thaliana maps to the N-terminal region of the coat protein.

29 Sep 2009 In Arabidopsis thaliana Columbia (Col-0) plants, the restriction of Tobacco etch virus (TEV) long-distance movement involves at least three dominant RTM (restricted TEV movement) genes named RTM1, RTM2, and RTM3. Previous work has established that, ... Read more...

Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells.

19 Sep 2009 Endoplasmic reticulum protein 29 (ERp29) is a novel endoplasmic reticulum (ER) secretion factor that facilitates the transport of secretory proteins in the early secretory pathway. Recently, it was found to be overexpressed in several cancers; ... Read more...

Latest indexed articles for 'Heat-Shock Proteins - Genetics'

These are the very latest articles for this heading:

• The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I. 29 Sep 2009
• The determinant of potyvirus ability to overcome the RTM resistance of Arabidopsis thaliana maps to the N-terminal region of the coat protein. 29 Sep 2009
• Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells. 19 Sep 2009
• Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. 16 Sep 2009
• Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors. 13 Sep 2009
• Single nucleotide polymorphism of rs430397 in the fifth intron of GRP78 gene and clinical relevance of primary hepatocellular carcinoma in Han Chinese: risk and prognosis. 13 Sep 2009
• [Mutation in the cspH-cspG gene cluster enhances expression of heat-shock proteins and SOS repair system of Escherichia coli] 30 Aug 2009
• Growing Bacillus subtilis tendrils sense and avoid each other. 30 Aug 2009
• Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. 30 Aug 2009
• GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib. 25 Aug 2009
• Substrate binding site flexibility of the small heat shock protein molecular chaperones. 24 Aug 2009
• Rice sHsp genes: genomic organization and expression profiling under stress and development. 22 Aug 2009
• Recombinant Listeria monocytogenes expressing a cell wall-associated listeriolysin O is weakly virulent but immunogenic. 8 Aug 2009
• The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. 8 Aug 2009
• Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. 5 Aug 2009
• Nucleotide binding and allosteric modulation of the second AAA+ domain of ClpB probed by transient kinetic studies. 2 Aug 2009
• The mysterious steps in carcinogenesis. 2 Aug 2009
• Protein kinase Mzeta maintains fear memory in the amygdala but not in the hippocampus. 30 Jul 2009
• Effect of dietary fat to produce non-alcoholic fatty liver in the rat. 30 Jul 2009
• Model-based evolutionary analysis: the natural history of phage-shock stress response. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Heat-Shock Proteins'

Definition: Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.

Registry Number: 0

Descriptor UI: D006360

Alternative terms: Heat-Shock Proteins; Heat Shock Proteins; Proteins, Heat-Shock; Stress Proteins; Proteins, Stress; Heat-Shock Protein; Heat Shock Protein; Protein, Heat-Shock; Stress Protein 71; Protein 71, Stress; Stress Protein 34; Protein 34, Stress; Heat-Shock Protein Chlamydomonas; Chlamydomonas, Heat-Shock Protein; Heat Shock Protein Chlamydomonas;

Related Mesh Headings: Molecular Chaperones;

Allowable Qualifiers: economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects;

Tree Number: D12.776.410;

History Note: 84

Technical Notes: /biosyn /drug eff /physiol /ultrastruct permitted; do not use /analogs