Heat-Shock Proteins - Metabolism
Research News and Information

Sunday, November 22, 2009

Prion protein and its ligand stress inducible protein 1 regulate astrocyte development.

29 Sep 2009 Prion protein (PrP(C)) interaction with stress inducible protein 1 (STI1) mediates neuronal survival and differentiation. However, the function of PrP(C) in astrocytes has not been approached. In this study, we show that STI1 prevents cell death in ... Read more...

Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells.

19 Sep 2009 Endoplasmic reticulum protein 29 (ERp29) is a novel endoplasmic reticulum (ER) secretion factor that facilitates the transport of secretory proteins in the early secretory pathway. Recently, it was found to be overexpressed in several cancers; ... Read more...

Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.

16 Sep 2009 The p62/sequestosome 1 protein has been identified as a component of pathological protein inclusions in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). P62 has also been implicated in autophagy, a process of mass ... Read more...

Latest indexed articles for 'Heat-Shock Proteins - Metabolism'

These are the very latest articles for this heading:

• Prion protein and its ligand stress inducible protein 1 regulate astrocyte development. 29 Sep 2009
• Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal-epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells. 19 Sep 2009
• Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. 16 Sep 2009
• Identification of novel spartin-interactors shows spartin is a multifunctional protein. 14 Sep 2009
• [Mutation in the cspH-cspG gene cluster enhances expression of heat-shock proteins and SOS repair system of Escherichia coli] 30 Aug 2009
• Expression of heat shock proteins in tissues from young pigs exposed to transport stress. 30 Aug 2009
• Radiofrequency radiation and gene/protein expression: a review. 30 Aug 2009
• Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle. 30 Aug 2009
• Regression of polypoid nasal mucosa after systemic corticosteroid therapy: a proteomics study. 29 Aug 2009
• Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead. 27 Aug 2009
• Substrate binding site flexibility of the small heat shock protein molecular chaperones. 24 Aug 2009
• Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha. 24 Aug 2009
• Rice sHsp genes: genomic organization and expression profiling under stress and development. 22 Aug 2009
• Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways. 18 Aug 2009
• DnaK-mediated association of ClpB to protein aggregates. A bichaperone network at the aggregate surface. 17 Aug 2009
• Ecotoxicological multilevel-evaluation of the effects of fenbendazole exposure to Chironomus riparius larvae. 12 Aug 2009
• The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. 8 Aug 2009
• Induction of protein body formation in plant leaves by elastin-like polypeptide fusions. 5 Aug 2009
• Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. 5 Aug 2009
• Cell biology. Lethal traffic jam. 5 Aug 2009

See a longer list of these articles.

Technical information about 'Heat-Shock Proteins'

Definition: Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.

Registry Number: 0

Descriptor UI: D006360

Alternative terms: Heat-Shock Proteins; Heat Shock Proteins; Proteins, Heat-Shock; Stress Proteins; Proteins, Stress; Heat-Shock Protein; Heat Shock Protein; Protein, Heat-Shock; Stress Protein 71; Protein 71, Stress; Stress Protein 34; Protein 34, Stress; Heat-Shock Protein Chlamydomonas; Chlamydomonas, Heat-Shock Protein; Heat Shock Protein Chlamydomonas;

Related Mesh Headings: Molecular Chaperones;

Allowable Qualifiers: economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects;

Tree Number: D12.776.410;

History Note: 84

Technical Notes: /biosyn /drug eff /physiol /ultrastruct permitted; do not use /analogs