Hematopoiesis - Drug effects
Research News and Information

Sunday, November 22, 2009

Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector.

29 Sep 2009 To assist in screening existing drugs for use as potential radioprotectors, we used a human unbiased 16,560 short interfering RNA (siRNA) library targeting the druggable genome. We performed a synthetic protection screen that was designed to ... Read more...

Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome.

24 Aug 2009 Thrombocytopenia is a frequent symptom and clinical challenge in patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Eltrombopag is a small molecule thrombopoietin receptor agonist that might be a new option to treat ... Read more...

Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease.

15 Jul 2009 Carbon monoxide (CO) has anti-inflammatory properties. We previously reported that acute treatments with inhaled CO inhibit vascular inflammation and hypoxia-induced vasoocclusion in sickle cell disease mouse models. Therefore, we hypothesized that ... Read more...

Latest indexed articles for 'Hematopoiesis - Drug effects'

These are the very latest articles for this heading:

• Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector. 29 Sep 2009
• Developmental biology: Instructions writ in blood. 8 Sep 2009
• Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. 24 Aug 2009
• [Toxic hematologic side effects of chemotherapy: nursing interventions] 30 Jul 2009
• Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease. 15 Jul 2009
• Protective effect of an extract from Periplaneta americana on hematopoiesis in irradiated rats. 29 Jun 2009
• Retinoids inhibit differentiation of hematopoietic osteoclast progenitors. 20 Jun 2009
• Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. 8 Jun 2009
• Role of the spleen in cyclophosphamide-induced hematosuppression and extramedullary hematopoiesis in mice. 2 Jun 2009
• Immunotoxicity profile of natalizumab. 30 May 2009
• Experimental study of the bone marrow protective effect of a traditional Chinese compound preparation. 30 May 2009
• Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems. 21 May 2009
• Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia. 18 May 2009
• Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. 3 May 2009
• [Chronic myeloid leukemia in the 21st century: biology and treatment] 29 Apr 2009
• An herbal decoction of Radix astragali and Radix angelicae sinensis promotes hematopoiesis and thrombopoiesis. 9 Apr 2009
• Chronic treatment with recombinant human erythropoietin exerts renoprotective effects beyond hematopoiesis in streptozotocin-induced diabetic rat. 3 Apr 2009
• Postnatal development in cynomolgus monkeys following prenatal exposure to natalizumab, an alpha4 integrin inhibitor. 30 Mar 2009
• Granulocyte-macrophage colony-stimulating factor gene based therapy for acute limb ischemia in a mouse model. 30 Mar 2009
• Choosing between GVHD and delayed engraftment. 30 Mar 2009

See a longer list of these articles.

Technical information about 'Hematopoiesis'

Definition: The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY).

Descriptor UI: D006410

Alternative terms: Hematopoiesis; Haematopoiesis; Hematopoiesis, Medullary; Medullary Hematopoiesis;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G04.299.151.825; G09.188.124.544;

Technical Notes: GEN or unspecified; prefer specifics