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Hemoglobin A, Glycosylated - Metabolism
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Definition of 'Hemoglobin A, Glycosylated'

Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.

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Saturday, November 21, 2009

Prediction of proliferative diabetic retinopathy with hemoglobin level.

30 Oct 2009 OBJECTIVE: To investigate the role of hemoglobin (HGB) level in predicting proliferative diabetic retinopathy (PDR). METHODS: We assessed 426 individuals without PDR at baseline (213 men; 213 women) from the Pittsburgh Epidemiology of Diabetes ... Read more...


A(1c) control in a primary care setting: self-titrating an insulin analog pre-mix (INITIATEplus trial).

30 Oct 2009 PURPOSE: To study glycemic control and hypoglycemia development upon initiation of insulin through a self-titration schedule in a 24-week trial, conducted with 4875 insulin-naïve patients with poorly controlled type 2 diabetes, predominantly in a ... Read more...


The effects of a nurse case manager and a community health worker team on diabetic control, emergency department visits, and hospitalizations among urban African Americans with type 2 diabetes mellitus: a randomized controlled trial.

24 Oct 2009 BACKGROUND: Although African American adults bear a disproportionate burden from diabetes mellitus (DM), few randomized controlled trials have tested culturally appropriate interventions to improve DM care. METHODS: We randomly assigned 542 African ... Read more...

 

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Technical information about 'Hemoglobin A, Glycosylated'

Definition: Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.

Registry Number: 0

Descriptor UI: D006442

Alternative terms: Hemoglobin A, Glycosylated; Hb A1a+b; Hb A1c; HbA1; Glycosylated Hemoglobin A; Hb A1; Glycohemoglobin A; Hemoglobin A(1); Hemoglobin, Glycosylated A1b; A1b Hemoglobin, Glycosylated; Glycosylated A1b Hemoglobin; Hb A1b; Hemoglobin, Glycosylated A1a-1; A1a-1 Hemoglobin, Glycosylated; Glycosylated A1a-1 Hemoglobin; Hemoglobin, Glycosylated A1a 1; Hb A1a-1; Hb A1a-2; Hemoglobin, Glycosylated; Glycosylated Hemoglobin; Glycated Hemoglobins; Hemoglobins, Glycated;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D09.408.375; D12.776.124.400.405.440; D12.776.422.316.762.380.440;

History Note: 82

Technical Notes: urine: coord IM with HEMOGLOBINURIA (IM); DF: note short X refs

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