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Hemophilia A
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Definition of 'Hemophilia A'

The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.

Common names: Hemophilia A; A, Hemophilia; As, Hemophilia; Hemophilia As; Haemophilia; Factor VIII Deficiency; Hemophilia; Deficiency, Factor VIII; Deficiencies, Factor VIII; Factor VIII Deficiencies

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Sunday, November 22, 2009

High frequencies of exposure to the novel human parvovirus PARV4 in hemophiliacs and injection drug users, as detected by a serological assay for PARV4 antibodies.

29 Sep 2009 BACKGROUND: PARV4 is a human parvovirus that was first detected in and cloned from an individual with a human immunodeficiency virus (HIV) seroconversion-like illness and that subsequently persisted in the lymphoid tissue and bone marrow. In ... Read more...


The clinical management of hemophilia and head trauma: a survey of current clinical practice among pediatric hematology/oncology physicians.

30 Aug 2009 BACKGROUND: Determining the appropriate evaluation for a pediatric patient with hemophilia and head trauma is a diagnostic challenge with no neuroimaging guidelines and limited clinical evidence to direct care. PROCEDURE: A questionnaire, with two ... Read more...


Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice.

2 Aug 2009 Recombinant FVIII formulated in PEG-ylated liposomes (rFVIII-PEG-Lip) was reported to increase the bleed-free days from 7 to 13 days (at 35 IU/kg rFVIII) in severe hemophilia A patients. To understand the underlying mechanism, we sought to ... Read more...

 

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Technical information about 'Hemophilia A'

Definition: The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.

Descriptor UI: D006467

Alternative terms: Hemophilia A; A, Hemophilia; As, Hemophilia; Hemophilia As; Haemophilia; Factor VIII Deficiency; Hemophilia; Deficiency, Factor VIII; Deficiencies, Factor VIII; Factor VIII Deficiencies;

Related Mesh Headings: Hemophilia B; Hemarthrosis;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C15.378.100.100.500; C15.378.100.141.500; C15.378.463.500; C16.320.099.500;

History Note: 99(66)

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