Hepacivirus - Metabolism
Research News and Information

Sunday, March 21, 2010

Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up.

29 Sep 2009 Hepatitis C associated hypolipidemia has been demonstrated in studies from Europe and Africa. In two linked studies, we evaluated the relationship between hepatitis C infection and treatment with lipid levels in an American cohort and determined the ... Read more...

Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells.

26 Sep 2009 AIM: To investigate effects of iron on oxidative stress, heme oxygenase-1 (HMOX1) and hepatitis C viral (HCV) expression in human hepatoma cells stably expressing HCV proteins. METHODS: Effects of iron on oxidative stress, HMOX1, and HCV expression ... Read more...

An escalating dose regimen of pegylated interferon and ribavirin in HCV cirrhotic patients referred for liver transplant.

13 Sep 2009 BACKGROUND: To lessen the severity of recurrent hepatitis C virus (HCV) postliver transplantation (post-LT) by treating HCV patients with cirrhosis, we assessed the safety and efficacy of an escalating dose pegylated interferon (PEG-IFN)/ribavirin ... Read more...

Latest indexed articles for 'Hepacivirus - Metabolism'

These are the very latest articles for this heading:

• Hepatitis C virus infection and its clearance alter circulating lipids: implications for long-term follow-up. 29 Sep 2009
• Iron increases HMOX1 and decreases hepatitis C viral expression in HCV-expressing cells. 26 Sep 2009
• An escalating dose regimen of pegylated interferon and ribavirin in HCV cirrhotic patients referred for liver transplant. 13 Sep 2009
• High incidence of multiple primary carcinomas in HCV-infected patients with oral squamous cell carcinoma. 30 Aug 2009
• A genome-wide genetic screen for host factors required for hepatitis C virus propagation. 25 Aug 2009
• Management of hepatitis C virus infection in HIV/HCV co-infected patients: clinical review. 12 Aug 2009
• The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo. 10 Aug 2009
• A conserved proline between domains II and III of hepatitis C virus NS5A influences both RNA replication and virus assembly. 3 Aug 2009
• Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway. 3 Aug 2009
• The autophagy machinery is required to initiate hepatitis C virus replication. Aug 2009
• The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites. Aug 2009
• Alcoholic liver disease and hepatitis C: a frequently underestimated combination. 26 Jul 2009
• Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. 20 Jul 2009
• Class III phosphatidylinositol 4-kinase alpha and beta are novel host factor regulators of hepatitis C virus replication. 13 Jul 2009
• Specific activation of 2'-5'oligoadenylate synthetase gene promoter by hepatitis C virus-core protein: a potential for developing hepatitis C virus targeting gene therapy. 5 Jul 2009
• Survival after liver transplantation for hepatocellular carcinoma in the model for end-stage liver disease and pre-model for end-stage liver disease eras and the independent impact of hepatitis C virus. 29 Jun 2009
• Early high peak hepatitis C viral load levels independently predict hepatitis C-related liver failure post-liver transplantation. 29 Jun 2009
• Older donors: mounting risks for the hepatitis C-infected liver transplant recipient? 29 Jun 2009
• Mevalonate pathway modulation is associated with hepatitis C virus RNA presence in peripheral blood mononuclear cells. 16 Jun 2009
• IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR. 16 Jun 2009

See a longer list of these articles.

Technical information about 'Hepacivirus'

Definition: A genus of FLAVIVIRIDAE causing parenterally-transmitted HEPATITIS C which is associated with transfusions and drug abuse. Hepatitis C virus is the type species.

Descriptor UI: D016174

Alternative terms: Hepacivirus; Hepaciviruses; Hepatitis C-Like Viruses; Hepatitis C Like Viruses; Hepatitis C-Like Virus; Hepatitis C virus; Hepatitis C viruses;

Allowable Qualifiers: classification; drug effects; enzymology; genetics; growth & development; immunology; isolation & purification; metabolism; pathogenicity; physiology; radiation effects; ultrastructure; chemistry;

Tree Number: B04.450.410; B04.820.250.475; B04.909.777.310.475;

History Note: 2002 (1991)

Technical Notes: infection = HEPATITIS C or HEPATITIS C, CHRONIC