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Hepatic Encephalopathy - Physiopathology
Research News and Information
Definition of 'Hepatic Encephalopathy'A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5) |
Sunday, November 22, 2009
29 Sep 2009 
Patients with minimal hepatic encephalopathy (MHE) have impaired driving skills, but association of MHE with motor vehicle crashes is unclear. Standard psychometric tests (SPT) or inhibitory control test (ICT) can be used to diagnose MHE. The aim ... Read more...
Neurotransmitter receptor imbalances in motor cortex and basal ganglia in hepatic encephalopathy.
Aug 2009 Hepatic encephalopathy (HE) in chronic liver disease is characterized by neuropsychiatric and motor disturbances and associated with a net increase of inhibitory neurotransmission. Though many studies, mostly carried out in animal models, have ... Read more...
Impairment of driving ability and neuropsychological function in patients with MHE disease.
30 Jul 2009 Minimal hepatitis encephalopathy (MHE) is a liver cirrhosis complication that does not show symptoms of overt hepatitis encephalopathy (OHE) but can be detected using specific complementary neuropsychological and neurophysiological evaluations. ... Read more...
Latest indexed articles for 'Hepatic Encephalopathy - Physiopathology'
These are the very latest articles for this heading:
- Minimal hepatic encephalopathy is associated with motor vehicle crashes: the reality beyond the driving test. 29 Sep 2009
- Neurotransmitter receptor imbalances in motor cortex and basal ganglia in hepatic encephalopathy. Aug 2009
- Impairment of driving ability and neuropsychological function in patients with MHE disease. 30 Jul 2009
- Prolonged exposure to ammonia increases extracellular glutamate in cultured rat astrocytes. 30 Jun 2009
- Hepatic encephalopathy: pathophysiology and emerging therapies. 29 Jun 2009
- MRI findings associated with acute liver failure.
14 Jun 2009 - Performance of the hepatic encephalopathy scoring algorithm in a clinical trial of patients with cirrhosis and severe hepatic encephalopathy. 30 May 2009
- Severity of organ failure is an independent predictor of intracranial hypertension in acute liver failure. 20 May 2009
- The cat with neurological manifestations of systemic disease. Key conditions impacting on the CNS. 29 Apr 2009
- Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: ibuprofen restores its motor activity. 29 Apr 2009
- Electroencephalographic analysis for the assessment of hepatic encephalopathy: comparison of non-parametric and parametric spectral estimation techniques. 15 Mar 2009
- RNA oxidation and zinc in hepatic encephalopathy and hyperammonemia. 14 Jan 2009
- Liver transplantation and neurological side effects. 11 Jan 2009
- A radiologic "alcohol breathalyzer" test. 11 Jan 2009
- Liver function test results and outcomes in children with acute liver failure due to dengue infection. 30 Dec 2008
- [Disturbed brain bioelectric activity in patients with liver encephalopathy and cirrhosis] 30 Dec 2008
- The liver, the brain and nitrogen metabolism. 22 Dec 2008
- Identifying the direct effects of ammonia on the brain. 21 Dec 2008
- Signaling factors in the mechanism of ammonia neurotoxicity. 21 Dec 2008
- Role of artificial liver support in hepatic encephalopathy. 19 Dec 2008
See a longer list of these articles.
Technical information about 'Hepatic Encephalopathy'
Definition: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
Descriptor UI: D006501
Alternative terms: Hepatic Encephalopathy; Encephalopathies, Hepatic; Hepatic Encephalopathies; Portal-Systemic Encephalopathy; Portal Systemic Encephalopathy; Encephalopathy, Portosystemic; Encephalopathy, Hepatic; Encephalopathy, Hepatocerebral; Encephalopathies, Hepatocerebral; Hepatocerebral Encephalopathies; Encephalopathy, Portal-Systemic; Encephalopathies, Portal-Systemic; Encephalopathy, Portal Systemic; Portal-Systemic Encephalopathies; Hepatocerebral Encephalopathy; Portosystemic Encephalopathy; Encephalopathies, Portosystemic; Portosystemic Encephalopathies; Hepatic Coma; Coma, Hepatic; Comas, Hepatic; Hepatic Comas; Hepatic Stupor; Hepatic Stupors; Stupor, Hepatic; Stupors, Hepatic; Fulminant Hepatic Failure with Cerebral Edema;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C06.552.308.500.356; C10.228.140.163.360; C18.452.132.360;
History Note: 1984; use HEPATIC COMA 1975-83