Hippocampus - Drug effects
Research News and Information

Saturday, November 21, 2009

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

Aberrant expression of synaptic plasticity-related genes in the NF1+/- mouse hippocampus.

30 Oct 2009 Neurofibromatosis 1 (NF1) is a common single-gene disorder that causes learning impairments in patients. Neurofibromin encoded by the NF1 causal gene regulates Ras/MAPK and cAMP signaling pathways. These signaling pathways play critical roles in ... Read more...

Contribution of Kv channel subunits to glutamate-induced apoptosis in cultured rat hippocampal neurons.

30 Oct 2009 Potassium channel dysfunction has been implicated in apoptosis in many pathological conditions. However, which Kv channel subunit is involved in glutamate-induced apoptosis remains unknown. In this study, the contributions of nine Kv alpha and three ... Read more...

Latest indexed articles for 'Hippocampus - Drug effects'

These are the very latest articles for this heading:

• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• Postmenopausal hormone therapy and regional brain volumes: the WHIMS-MRI study. Nov 2009
• Aberrant expression of synaptic plasticity-related genes in the NF1+/- mouse hippocampus. 30 Oct 2009
• Contribution of Kv channel subunits to glutamate-induced apoptosis in cultured rat hippocampal neurons. 30 Oct 2009
• Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade. 30 Oct 2009
• High fat and highly thermolyzed fat diets promote insulin resistance and increase DNA damage in rats. 30 Oct 2009
• Alteration of theta timescale dynamics of hippocampal place cells by a cannabinoid is associated with memory impairment. 5 Oct 2009
• Lysosomal modulatory drugs for a broad strategy against protein accumulation disorders. 29 Sep 2009
• MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning. 29 Sep 2009
• Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation. 29 Sep 2009
• c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues. 29 Sep 2009
• DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition. 29 Sep 2009
• A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis. 21 Sep 2009
• Dopamine enables in vivo synaptic plasticity associated with the addictive drug nicotine. 8 Sep 2009
• Nicotine's Allure. 8 Sep 2009
• Inbred mouse strains differ in multiple hippocampal activity traits. 2 Sep 2009
• Lack of kainic acid-induced gamma oscillations predicts subsequent CA1 excitotoxic cell death. 2 Sep 2009
• Activation of nicotinic acetylcholine receptors enhances a slow calcium-dependent potassium conductance and reduces the firing of stratum oriens interneurons. 2 Sep 2009
• Reelin signaling antagonizes beta-amyloid at the synapse. 31 Aug 2009
• BDNF and NT-3 increase excitatory input connectivity in rat hippocampal cultures. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Hippocampus'

Definition: A curved elevation of gray matter extending the entire length of the floor of the temporal horn of the lateral ventricle (Dorland, 28th ed). The hippocampus, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.

Descriptor UI: D006624

Alternative terms: Hippocampus; Cornu Ammonis; Ammon Horn; Horn, Ammon; Ammon's Horn; Ammons Horn; Horn, Ammon's; Subiculum; Subiculums; Hippocampal Formation; Formation, Hippocampal; Formations, Hippocampal; Hippocampal Formations;

Related Mesh Headings: Entorhinal Cortex; Perforant Pathway;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.464.405; A08.186.211.730.885.287.500.345;