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Histamine Antagonists - Administration & dosage
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Definition of 'Histamine Antagonists'

Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.

Common names: Histamine Antagonists; Antagonists, Histamine; Antihistamines

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Tuesday, November 24, 2009

Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity.

22 Sep 2009 Antagonism of the histamine-H(3) receptor is one tactic being explored to increase wakefulness for the treatment of disorders such as excessive daytime sleepiness (EDS) as well as other sleep or cognitive disorders. Phenethyl-R-2-methylpyrrolidine ... Read more...


Allergic contact dermatitis in children: common allergens and treatment: a review.

30 Jul 2009 PURPOSE OF REVIEW: The following study reviews the recent literature pertaining to allergic contact dermatitis (ACD) in the pediatric population. This study also provides an overview of the most common allergens and discusses various therapeutic ... Read more...


[Antipruritic efficacy of a high-dosage antihistamine therapy. Results of a retrospectively analysed case series]

29 Jun 2009 BACKGROUND AND OBJECTIVES: The causal treatment of chronic pruritus is not always possible or effective necessitating symptomatic antipruritic therapy. Antihistamines are the only drugs approved for the treatment of chronic pruritus, but they are ... Read more...

 

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Technical information about 'Histamine Antagonists'

Definition: Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.

Registry Number: 0

Descriptor UI: D006633

Alternative terms: Histamine Antagonists; Antagonists, Histamine; Antihistamines;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Tree Number: D27.505.519.625.375.425; D27.505.696.577.375.425;

History Note: 1977; for ANTIHISTAMINES use HISTAMINE H1 ANTAGONISTS 1997-2008

Technical Notes: GEN or unspecified; prefer specifics; do not confuse with HISTAMINE AGONISTS; DF: HISTAMINE ANTAG

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