Histamine Antagonists
Research News and Information

Sunday, November 22, 2009

Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.

29 Sep 2009 Many medicines exist which can cause pruritus (itching) as "serious adverse events." Many severe pruritic conditions respond poorly to histamine H1 receptor antagonists; there is no generally accepted antipruritic treatment. Recently described ... Read more...

Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity.

22 Sep 2009 Antagonism of the histamine-H(3) receptor is one tactic being explored to increase wakefulness for the treatment of disorders such as excessive daytime sleepiness (EDS) as well as other sleep or cognitive disorders. Phenethyl-R-2-methylpyrrolidine ... Read more...

Common immune-related risk factors and incident non-Hodgkin lymphoma: the multiethnic cohort.

13 Sep 2009 Severe immune dysfunction is an established risk factor of lymphoma, but the role of moderate alterations of immunity is not clear and prospective investigations are needed. We examined several immune-related disorders and medications in relation to ... Read more...

Latest indexed articles for 'Histamine Antagonists'

These are the very latest articles for this heading:

• Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist. 29 Sep 2009
• Central serous chorioretinopathy and idiopathic nonhistaminergic angioedema. 29 Sep 2009
• Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity. 22 Sep 2009
• Common immune-related risk factors and incident non-Hodgkin lymphoma: the multiethnic cohort. 13 Sep 2009
• Emerging drugs for conjunctivitis. 30 Aug 2009
• Emerging drugs for insomnia: new frontiers for old and novel targets. 30 Aug 2009
• Pharmacologic consideration of commonly used gastrointestinal drugs in the elderly. 30 Aug 2009
• Best drugs for what ails you: the brands to buy--and those to skip. 30 Aug 2009
• Antihistamines for anaphylaxis? Primary outcome measures. 16 Aug 2009
• Allergic rhinitis: background, symptoms, diagnosis and treatment options. 30 Jul 2009
• Emergency management of anaphylaxis in children and young people: new guidance from the Resuscitation Council (UK). 30 Jul 2009
• Allergic contact dermatitis in children: common allergens and treatment: a review. 30 Jul 2009
• Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome. 26 Jul 2009
• Ambroxol-induced systemic contact dermatitis confirmed by positive patch test. 21 Jul 2009
• Should antihistamines be used to treat anaphylaxis? 8 Jul 2009
• The first asymmetric halogen/metal-exchange reaction: desymmetrization of alcohols with enantiotopic bromoarene substituents. 4 Jul 2009
• [Urticaria pigmentosa: a current approach] 29 Jun 2009
• Intranasal corticosteroids: do they improve ocular allergy? 29 Jun 2009
• Hereditary angioedema with normal c1 inhibition. 29 Jun 2009
• [Antipruritic efficacy of a high-dosage antihistamine therapy. Results of a retrospectively analysed case series] 29 Jun 2009

See a longer list of these articles.

Technical information about 'Histamine Antagonists'

Definition: Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.

Registry Number: 0

Descriptor UI: D006633

Alternative terms: Histamine Antagonists; Antagonists, Histamine; Antihistamines;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Tree Number: D27.505.519.625.375.425; D27.505.696.577.375.425;

History Note: 1977; for ANTIHISTAMINES use HISTAMINE H1 ANTAGONISTS 1997-2008

Technical Notes: GEN or unspecified; prefer specifics; do not confuse with HISTAMINE AGONISTS; DF: HISTAMINE ANTAG