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HLA Antigens - Blood
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Definition of 'HLA Antigens'

Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.

Common names: HLA Antigens; Antigens, HLA; HL-A Antigens; Antigens, HL-A; HL A Antigens; Human Leukocyte Antigens; Antigens, Human Leukocyte; Leukocyte Antigens, Human; Leukocyte Antigens; Antigens, Leukocyte

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Monday, March 22, 2010

Induction of both membrane-bound and soluble HLA-G expression in active human cytomegalovirus infection.

30 Aug 2009 BACKGROUND: Alteration of HLA expression or cytokine production plays a crucial role in the pathogenesis of human cytomegalovirus (HCMV) infection. HLA-G has been suggested to be involved in HCMV infection, and modulation of HLA-G expression by ... Read more...


Women with pre-eclampsia have an altered NKG2A and NKG2C receptor expression on peripheral blood natural killer cells.

30 Aug 2009 PROBLEM: Preeclampsia, a pregnancy disorder, is associated with exaggerated inflammation and increased serum monokines. Uterine natural killer (NK) cells are implicated in preeclampsia pathology, but little is known regarding peripheral NK cells in ... Read more...


A lifetime versus a graft life approach redefines the importance of HLA matching in kidney transplant patients.

13 Jul 2009 INTRODUCTION: Human leukocyte antigen (HLA) matching has been de-emphasized in the allocation of renal allografts and further discounting is planned in the new United Network of Organ Sharing kidney allocation model. An unforeseen consequence of ... Read more...

 

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Technical information about 'HLA Antigens'

Definition: Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.

Registry Number: 0

Descriptor UI: D006680

Alternative terms: HLA Antigens; Antigens, HLA; HL-A Antigens; Antigens, HL-A; HL A Antigens; Human Leukocyte Antigens; Antigens, Human Leukocyte; Leukocyte Antigens, Human; Leukocyte Antigens; Antigens, Leukocyte;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D23.050.301.500.450; D23.050.705.552.450;

Online Note: use HLA ANTIGENS to search HL-A ANTIGENS 1978-81 and HL-A 1975-77; use HISTOCOMPATIBILITY ANTIGENS to search HL-A 1974

History Note: 82; was HL-A ANTIGENS 1978-81; was HL-A see under HISTOCOMPATIBILITY ANTIGENS 1974-77

Technical Notes: human only, standing for Human Leukocyte Antigen; assoc with tissue types in transpl & with various dis; GEN or unspecified; prefer specifics; HLA goes here; DF: HLA

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