HLA-B Antigens - Immunology
Research News and Information

Sunday, November 22, 2009

An approach to predicting hematopoietic stem cell transplantation outcome using HLA-mismatch information mapped on protein structure data.

30 Aug 2009 In hematopoietic stem cell transplantation (HSCT), the outcome is predicted using HLA-matching procedures, which are very time-consuming. There exists substantial evidence of the importance of early donor acceptance in HSCT outcome. In cases when ... Read more...

HLA-B27 and HLA-B51 determination in Tunisian healthy subjects and patients with suspected ankylosing spondylitis and Behçet's disease.

30 Aug 2009 The aim of this retrospective study is to assess the frequency of HLA-B27 and HLA-B51 in healthy subjects from the center of Tunisia and to investigate their usefulness in the diagnosis of ankylosing spondylitis (AS) and Behçet's disease (BD), ... Read more...

Novel HIV-1 clade B candidate vaccines designed for HLA-B*5101(+) patients protected mice against chimaeric ecotropic HIV-1 challenge.

29 Jun 2009 Novel candidate HIV-1 vaccines have been constructed, which are tailor-designed for HLA-B*5101(+) patients infected with HIV-1 clade B. These vaccines employ novel immunogen HIVB-B*5101 derived from consensus HIV-1 clade B Gag p17 and p24 regions ... Read more...

Latest indexed articles for 'HLA-B Antigens - Immunology'

These are the very latest articles for this heading:

• An approach to predicting hematopoietic stem cell transplantation outcome using HLA-mismatch information mapped on protein structure data. 30 Aug 2009
• HLA-B27 and HLA-B51 determination in Tunisian healthy subjects and patients with suspected ankylosing spondylitis and Behçet's disease. 30 Aug 2009
• Foreword. Drug allergy and primum non-nocere. 30 Jul 2009
• Novel HIV-1 clade B candidate vaccines designed for HLA-B*5101(+) patients protected mice against chimaeric ecotropic HIV-1 challenge. 29 Jun 2009
• The convenience of flow cytometry for HLA-B*5701 screening to prevent abacavir hypersensitivity reactions. 29 Jun 2009
• Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant. 8 Jun 2009
• Correlations between Terasaki's HLA class I epitopes and HLAMatchmaker-defined eplets on HLA-A, -B and -C antigens. 31 May 2009
• Comparison of combination Plasmapheresis/IVIg/anti-CD20 versus high-dose IVIg in the treatment of antibody-mediated rejection. 29 Apr 2009
• Association of various inflammatory diseases with human leukocyte antigens B27, B7, Bw4 and Bw6 in patients with SSA. 24 Apr 2009
• Association of TLR4 polymorphisms with Behcet's disease in a Korean population. 22 Apr 2009
• HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection. 20 Apr 2009
• Effective downregulation of HLA-A*2 and HLA-B*57 by primary human immunodeficiency virus type 1 isolates cultured from elite suppressors. 20 Apr 2009
• BCR/ABL-specific CD8+ T cells can be detected from CML patients, but are only expanded from healthy donors. 8 Apr 2009
• Genetic basis for idiosyncratic reactions to antiepileptic drugs. 30 Mar 2009
• Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation. 30 Mar 2009
• [Immunogenetic criteria for prediction of mixed hepatitis A + B] 30 Mar 2009
• Assessment of the amino acid substitution in HLA-B*5719 for allorecognition. 30 Mar 2009
• Preferential expansion of human umbilical cord blood-derived CD34-positive cells on major histocompatibility complex-matched amnion-derived mesenchymal stem cells. 29 Mar 2009
• A reevaluation of the role of IgM Non-HLA antibodies in cardiac transplantation. 25 Mar 2009
• Behçet's disease--a contemporary review. 24 Mar 2009

See a longer list of these articles.

Technical information about 'HLA-B Antigens'

Definition: Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.

Registry Number: 0

Descriptor UI: D015235

Alternative terms: HLA-B Antigens; HLA B Antigens; HLA-B; Antigens, HLA-B; Antigens, HLA B;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacology; physiology; poisoning; radiation effects; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D23.050.301.500.400.380; D23.050.301.500.450.380; D23.050.705.552.400.380; D23.050.705.552.450.380;

History Note: 89

Technical Notes: assoc with predisposition to rheumatoid & other autoimmune disord; DF: HLA B