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Hodgkin Disease - Research News and Information

Saturday, January 10, 2009

Definition of 'Hodgkin Disease'

A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.

Common names: Hodgkin Disease; Disease, Hodgkin; Hodgkins Disease; Disease, Hodgkins; Diseases, Hodgkins; Hodgkins Diseases; Hodgkin's Lymphoma; Hodgkin's Lymphomas; Hodgkins Lymphoma; Lymphoma, Hodgkin's; Lymphomas, Hodgkin's; Lymphogranuloma, Malignant; Lymphogranulomas, Malignant; Malignant Lymphogranuloma

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Scholastic achievement of children with lymphoma or Wilms tumor at the end of comprehensive education--a nationwide, register-based study.

13 Nov 2008 Cancer treatment may affect school performance. School report grades after childhood lymphomas and Wilms tumor have not been previously reported. All Finnish patients with Wilms tumor (N = 74), Hodgkin lymphoma (HL) (N = 99) and non-Hodgkin ... Read more...


Evidence for a pathophysiological role of cysteinyl leukotrienes in classical Hodgkin lymphoma.

13 Nov 2008 Classical Hodgkin lymphoma (cHL) is characterized histologically by a minority of malignant Hodgkin Reed-Sternberg cells surrounded by abundant inflammatory cells, generally believed to be of major importance in the pathophysiology of the disease. ... Read more...


BCL2 and BCL3 are recurrent translocation partners of the IGH locus.

13 Oct 2008 Chromosomal translocations affecting the immunoglobulin heavy chain (IGH) locus in chromosomal band 14q32 are the most frequent cytogenetic changes in B-cell lymphomas. We studied the presence of IGH translocations in a consecutively ascertained ... Read more...

 

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Technical information about 'Hodgkin Disease'

Definition: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.

Descriptor UI: D006689

Alternative terms: Hodgkin Disease; Disease, Hodgkin; Hodgkins Disease; Disease, Hodgkins; Diseases, Hodgkins; Hodgkins Diseases; Hodgkin's Lymphoma; Hodgkin's Lymphomas; Hodgkins Lymphoma; Lymphoma, Hodgkin's; Lymphomas, Hodgkin's; Lymphogranuloma, Malignant; Lymphogranulomas, Malignant; Malignant Lymphogranuloma; Malignant Lymphogranulomas; Hodgkin Lymphoma; Hodgkin Lymphomas; Lymphoma, Hodgkin; Lymphomas, Hodgkin; Hodgkin's Disease; Disease, Hodgkin's; Granuloma, Hodgkin's; Hodgkin's Granuloma; Granuloma, Hodgkin; Hodgkin Granuloma; Granuloma, Malignant; Malignant Granuloma; Malignant Granulomas; Granuloma, Hodgkins; Hodgkins Granuloma;

Related Mesh Headings: Reed-Sternberg Cells;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C04.557.386.355; C15.604.515.569.355; C20.683.515.761.355;

History Note: 98(66)

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